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Title:
OPIOID RECEPTOR AGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/030319
Kind Code:
A1
Abstract:
An oxa-spiro small-molecule compound, a preparation method therefor, a pharmaceutical composition containing the compound, and the use thereof as an MOR receptor agonist and in the preparation of a drug for treating and/or preventing diseases related pain, etc.

Inventors:
LUO MING (CN)
NIE YUEKUN (CN)
CHEN HAIWEN (CN)
LI XINXING (CN)
QI LINGBO (CN)
LIU JUNHUA (CN)
SONG ZHILIN (CN)
Application Number:
PCT/CN2022/115846
Publication Date:
March 09, 2023
Filing Date:
August 30, 2022
Export Citation:
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Assignee:
HINYE PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D409/14; A61K31/4427; A61K31/537; A61P29/00; C07D405/04; C07D405/14; C07D409/12; C07D493/10; C07D495/04
Domestic Patent References:
WO2022033380A12022-02-17
WO2017105881A12017-06-22
Foreign References:
CN108601775A2018-09-28
CN108366997A2018-08-03
CN103702561A2014-04-02
CN109206417A2019-01-15
CN109516982A2019-03-26
CN106588899A2017-04-26
CN109689646A2019-04-26
Attorney, Agent or Firm:
PATENTSINO IP FIRM (CN)
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