Title:
ORAL NEISSERIA-MUCOSA-INCREASING AGENT
Document Type and Number:
WIPO Patent Application WO/2022/202403
Kind Code:
A1
Abstract:
Provided is a material that is useful for increasing the Neisseria mucosa content in the oral cavity. This oral Neisseria-mucosa-increasing agent has, as active ingredients, a nitrate-ion-supplying compound and one or more sugar alcohols selected from erythritol, xylitol, and mannitol.
Inventors:
FUJII AKIHIKO (JP)
AKATSU TOMOKI (JP)
KAWANO SAWAKO (JP)
SONO HATSUMI (JP)
MINEGISHI YOSHIHIKO (JP)
AKATSU TOMOKI (JP)
KAWANO SAWAKO (JP)
SONO HATSUMI (JP)
MINEGISHI YOSHIHIKO (JP)
Application Number:
PCT/JP2022/010902
Publication Date:
September 29, 2022
Filing Date:
March 11, 2022
Export Citation:
Assignee:
KAO CORP (JP)
International Classes:
A61K33/00; A23L33/125; A61K8/19; A61K8/34; A61K31/047; A61K47/26; A61P1/02; A61P9/12; A61P21/00; A61P31/02; A61P31/04; A61P43/00; A61Q11/00
Domestic Patent References:
| WO2017002891A1 | 2017-01-05 |
Foreign References:
| JP2012188377A | 2012-10-04 | |||
| JP2011105690A | 2011-06-02 | |||
| JP2004026816A | 2004-01-29 | |||
| US20160151428A1 | 2016-06-02 | |||
| JP2021020869A | 2021-02-18 | |||
| JP2015157768A | 2015-09-03 | |||
| JP2018530517A | 2018-10-18 |
Other References:
ONYANGO STANLEY O., DE CLERCQ NELE, BEERENS KOEN, VAN CAMP JOHN, DESMET TOM, VAN DE WIELE TOM: "Oral Microbiota Display Profound Differential Metabolic Kinetics and Community Shifts upon Incubation with Sucrose, Trehalose, Kojibiose, and Xylitol", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 86, no. 16, 3 August 2020 (2020-08-03), US , pages 1 - 14, XP055970801, ISSN: 0099-2240, DOI: 10.1128/AEM.01170-20
BARTH KENNETH R., ISABELLA VINCENT M., CLARK VIRGINIA L.: "Biochemical and genomic analysis of the denitrification pathway within the genus Neisseria", MICROBIOLOGY, SOCIETY FOR GENERAL MICROBIOLOGY, READING, vol. 155, no. 12, 1 December 2009 (2009-12-01), Reading , pages 4093 - 4103, XP055970803, ISSN: 1350-0872, DOI: 10.1099/mic.0.032961-0
EMBRIETTE R. HYDE, FERNANDO ANDRADE, ZALMAN VAKSMAN, KAVITHA PARTHASARATHY, HONG JIANG, DEEPA K. PARTHASARATHY, ASHLEY C. TORREGRO: "Metagenomic Analysis of Nitrate-Reducing Bacteria in the Oral Cavity: Implications for Nitric Oxide Homeostasis", PLOS ONE, vol. 9, no. 3, pages e88645, XP055289203, DOI: 10.1371/journal.pone.0088645
BARTH KENNETH R., ISABELLA VINCENT M., CLARK VIRGINIA L.: "Biochemical and genomic analysis of the denitrification pathway within the genus Neisseria", MICROBIOLOGY, SOCIETY FOR GENERAL MICROBIOLOGY, READING, vol. 155, no. 12, 1 December 2009 (2009-12-01), Reading , pages 4093 - 4103, XP055970803, ISSN: 1350-0872, DOI: 10.1099/mic.0.032961-0
EMBRIETTE R. HYDE, FERNANDO ANDRADE, ZALMAN VAKSMAN, KAVITHA PARTHASARATHY, HONG JIANG, DEEPA K. PARTHASARATHY, ASHLEY C. TORREGRO: "Metagenomic Analysis of Nitrate-Reducing Bacteria in the Oral Cavity: Implications for Nitric Oxide Homeostasis", PLOS ONE, vol. 9, no. 3, pages e88645, XP055289203, DOI: 10.1371/journal.pone.0088645
Attorney, Agent or Firm:
THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)
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