Title:
ORALLY ACTIVE SALTS WITH TYROSINE KINASE ACTIVITY
Document Type and Number:
WIPO Patent Application WO2002032861
Kind Code:
A3
Abstract:
The present invention relates to orally active salts of compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis, cancer, tumor growth, atherosclerosis, age related macular degeneration, diabetic retinopathy, inflammatory diseases, and the like in mammals.
Inventors:
FRALEY MARK E (US)
KARKI SHYAM B (US)
KIM YUNTAE (US)
KARKI SHYAM B (US)
KIM YUNTAE (US)
Application Number:
PCT/US2001/032508
Publication Date:
August 15, 2002
Filing Date:
October 17, 2001
Export Citation:
Assignee:
MERCK & CO INC (US)
FRALEY MARK E (US)
KARKI SHYAM B (US)
KIM YUNTAE (US)
FRALEY MARK E (US)
KARKI SHYAM B (US)
KIM YUNTAE (US)
International Classes:
A61K31/4709; A61K31/496; A61K31/551; A61P3/10; A61P9/00; A61P17/00; A61P17/06; A61P19/02; A61P27/02; A61P29/00; A61P35/00; A61P43/00; C07D401/04; C07D401/14; (IPC1-7): C07D241/04; C07D243/06; C07D401/04; A61K31/4704; A61K31/496; A61K31/551
Foreign References:
| US5409930A | 1995-04-25 |
Other References:
See also references of EP 1328519A4
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