PROCESS FOR PRODUCING alpha-ALKOXYIMINOPHENYLACETONITRILE DERIVATIVE

Title:

PROCESS FOR PRODUCING alpha-ALKOXYIMINOPHENYLACETONITRILE DERIVATIVE

Document Type and Number:

WIPO Patent Application WO/1995/001330

Kind Code:

A1

Abstract:

A process for producing an alpha-alkoxyiminophenylacetonitrile represented by general formula [III], (wherein R1, R2, R3 and Y are each as defined in the specification) by reacting an alkali metal salt of an alpha-hydroxyiminophenylacetonitrile, represented by general formula [I], (wherein R1, R2, Y and A are each as defined in the specification) with a dialkyl sulfate represented by the general formula [II]: (R3)2SO4, (wherein R3 is as defined in the specification) in the presence of a phase transfer catalyst in a solvent mixture composed of a hydrocarbon solvent and water. It is possible by using the above catalyst and solvent mixture to inhibit the formation of a nitrone derivative as a by-product to thereby produce a highly pure alkoxyimino compound in a high yield.

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Inventors:

TAKASE AKIRA (JP)
KAI HIROYUKI (JP)
MASUI MORIYASU (JP)
MASUMOTO KATUHISA (JP)
NAKAMURA AKIHIKO (JP)
KIYOSHIMA YUJIRO (JP)
SASAKI MIKIO (JP)

Application Number:

PCT/JP1994/001077

Publication Date:

January 12, 1995

Filing Date:

July 01, 1994

Export Citation:

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Assignee:

SHIONOGI & CO (JP)
SUMITOMO CHEMICAL CO (JP)
TAKASE AKIRA (JP)
KAI HIROYUKI (JP)
MASUI MORIYASU (JP)
MASUMOTO KATUHISA (JP)
NAKAMURA AKIHIKO (JP)
KIYOSHIMA YUJIRO (JP)
SASAKI MIKIO (JP)

International Classes:

C07C251/48; C07C253/30; C07C255/61; C07C319/20; (IPC1-7): C07C255/62; C07C253/30; C07C323/63; C07C319/20

Foreign References:

JPH0489464A	1992-03-23
JPH06219986A	1994-08-09

Other References: