Title:
PEPTIDE ANTIGENS
Document Type and Number:
WIPO Patent Application WO2001040264
Kind Code:
A9
Abstract:
The present invention provides compositions and methods for reducing the severity and/or number of allergic symptoms in individuals sensitive to one or more antigens. In general, the inventive compositions comprise fragments of antigens and are characterized by a reduced ability to bind to anti-antigen IgE. Preferred compositions comprise overlapping fragments that together represent substantially all of the structural features of the relevant antigen except that one or more IgE binding sites may be omitted. Particularly preferred compositions comprise fragments of anaphylactic antigens, especially food antigens such as peanut antigens or shellfish antigens.
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Inventors:
BANNON GARY A
BURKS WESLEY A
CAPLAN MICHAEL J
SAMPSON HUGH
SOSIN HOWARD
BURKS WESLEY A
CAPLAN MICHAEL J
SAMPSON HUGH
SOSIN HOWARD
Application Number:
PCT/US2000/033124
Publication Date:
May 30, 2002
Filing Date:
December 06, 2000
Export Citation:
Assignee:
PANACEA PHARM LLC (US)
UNIV ARKANSAS (US)
SINAI SCHOOL MEDICINE (US)
UNIV ARKANSAS (US)
SINAI SCHOOL MEDICINE (US)
International Classes:
A01K67/027; A61K39/35; A61K39/36; A61K39/38; C07K14/415; A61K38/095; A61K39/00; (IPC1-7): C07K14/415; C07K7/08; A61K39/35; A01K67/02; G01N33/68
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