Title:
PHARMACEUTICAL COMPOSITION AND MANUFACTURING METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2013/038997
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide: a pharmaceutical composition comprising a human serum enzyme-treated product that is useful for treating or preventing diseases such as cancer and infections; and a method for manufacturing said pharmaceutical composition. The present invention pertains to: a method for manufacturing a pharmaceutical composition comprising a human serum enzyme-treated product, said manufacturing method including a step for bringing human serum into contact with β-galactosidase; and a pharmaceutical composition comprising a human serum enzyme-treated product obtained according to said manufacturing method.
Inventors:
UTO YOSHIHIRO (JP)
HORI HITOSHI (JP)
INUI TOSHIO (JP)
KUBO KENTARO (JP)
HORI HITOSHI (JP)
INUI TOSHIO (JP)
KUBO KENTARO (JP)
Application Number:
PCT/JP2012/072884
Publication Date:
March 21, 2013
Filing Date:
September 07, 2012
Export Citation:
Assignee:
SAISEI MIRAI CLINIC (JP)
UNIV TOKUSHIMA (JP)
UTO YOSHIHIRO (JP)
HORI HITOSHI (JP)
INUI TOSHIO (JP)
KUBO KENTARO (JP)
UNIV TOKUSHIMA (JP)
UTO YOSHIHIRO (JP)
HORI HITOSHI (JP)
INUI TOSHIO (JP)
KUBO KENTARO (JP)
International Classes:
A61K35/16; A61P31/00; A61P35/00
Domestic Patent References:
| WO2012029954A1 | 2012-03-08 |
Foreign References:
| JPH0597695A | 1993-04-20 | |||
| JPH0699314B2 | 1994-12-07 |
Other References:
YAMAMOTO N ET AL.: "Role of vitamin D3-binding protein in activation of mouse macrophages", THE JOURNAL OF IMMUNOLOGY, vol. 157, no. 4, 15 August 1996 (1996-08-15), pages 1744 - 1749, XP055122334
YAMAMOTO N ET AL.: "Vitamin D3 binding protein (group-specific component) is a precursor for the macrophage-activating signal factor from lysophosphatidylcholine-treated lymphocytes", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 88, no. 19, 1 October 1991 (1991-10-01), pages 8539 - 8543, XP002145254
HITOSHI HORI ET AL.: "Gc Tanpakushitsu (Vitamin D Ketsugo Tanpakushitsu) no Tosa Processing o Base to shita Dramatype Gan Chiryoyaku no Sosei", RADIATION BIOLOGY RESEARCH COMMUNICATIONS, vol. 39, no. 3, 29 September 2004 (2004-09-29), pages 328 - 341, XP008171071
YAMAMOTO N ET AL.: "Immunotherapy of HIV- infected patients with Gc protein-derived macrophage activating factor (GcMAF)", JOURNAL OF MEDICAL VIROLOGY, vol. 81, no. 1, January 2009 (2009-01-01), pages 16 - 26, XP055010289
See also references of EP 2687218A4
YAMAMOTO N ET AL.: "Vitamin D3 binding protein (group-specific component) is a precursor for the macrophage-activating signal factor from lysophosphatidylcholine-treated lymphocytes", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 88, no. 19, 1 October 1991 (1991-10-01), pages 8539 - 8543, XP002145254
HITOSHI HORI ET AL.: "Gc Tanpakushitsu (Vitamin D Ketsugo Tanpakushitsu) no Tosa Processing o Base to shita Dramatype Gan Chiryoyaku no Sosei", RADIATION BIOLOGY RESEARCH COMMUNICATIONS, vol. 39, no. 3, 29 September 2004 (2004-09-29), pages 328 - 341, XP008171071
YAMAMOTO N ET AL.: "Immunotherapy of HIV- infected patients with Gc protein-derived macrophage activating factor (GcMAF)", JOURNAL OF MEDICAL VIROLOGY, vol. 81, no. 1, January 2009 (2009-01-01), pages 16 - 26, XP055010289
See also references of EP 2687218A4
Attorney, Agent or Firm:
KAWAMURA, Kiyoshi et al. (JP)
Kiyoshi Kawamura (JP)
Kiyoshi Kawamura (JP)
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Claims: