Title:
PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING TREATMENT-RESISTANT CANCER
Document Type and Number:
WIPO Patent Application WO/2020/218562
Kind Code:
A1
Abstract:
Provided are a pharmaceutical composition for treating or preventing drug-resistant cancer by photodynamic therapy (PDT) that contains 5-aminolevulinic acid (ALA) or a derivative thereof, or a salt of these, and a method for treating or preventing drug-resistant cancer using the pharmaceutical composition.
Inventors:
KOHASHI MASAYUKI (JP)
HARADA YASUO (JP)
HARADA YASUO (JP)
Application Number:
PCT/JP2020/017805
Publication Date:
October 29, 2020
Filing Date:
April 24, 2020
Export Citation:
Assignee:
JIMRO CO LTD (JP)
International Classes:
A61P35/00; A61K31/195; A61K41/00
Domestic Patent References:
| WO2015125732A1 | 2015-08-27 | |||
| WO2015125732A1 | 2015-08-27 |
Foreign References:
| JP2005132766A | 2005-05-26 | |||
| JP2017513952A | 2017-06-01 |
Other References:
TAKAHASHI; H; ISHIDA-YAMAMOTO; A; NAKAJIMA; S; SAKATA; I; IIZUKA; H: "ATX-S10(Na)- photodynamic therapy inhibits cytokine secretion and proliferation of lymphocytes", JOURNAL OF DERMATOLOGICAL SCIENCE, vol. 49, no. 2, 24 December 2007 (2007-12-24), pages 174 - 177, XP022401023, ISSN: 0923-1811, DOI: 10.1016/j.jdermsci. 2007.07.015
LINGLING XU; ZHANG XUEQING; CHENG WENZHAO; WANG YONG; YI KAINING; WANG ZHILONG; ZHANG YILING; SHAO LINXIANG; ZHAO TIEJUN: "Hypericin-photodynamic therapy inhibits the growth of adult T- cell leukemia cells through induction of apoptosis and suppression of viral transcription", RETROVIROLOGY, vol. 16, 5, 19 February 2019 (2019-02-19), pages 1 - 13, XP055758340, DOI: 10.1186/s12977-019-0467-0
SIRINART CHIO-SRICHAN, OUDRHIRI NOUFISSA, BENNACEUR-GRISCELLI ANNELISE, TURHAN ALI G., DUMAS PAUL, REFREGIERS MATTHIEU: "Toxicity and phototoxicity of hypocrellin A on malignant human cell lines, evidence of a synergistic action of photodynamic therapy with Imatinib mesylate", JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B: BIOLOGY, vol. 99, no. 2, 2010306, pages 100 - 104, XP055759228, ISSN: 1011-1344, DOI: 10.1016/j.jphotobiol. 2010.03.001
TAKASHI OKA; MIZUNO HAJIME; SAKATA MASUMI; FUJITA HIROFUMI; YOSHINO TADASHI; YAMANO YOSHIHISA; UTSUMI KOZO; MASUJIMA TSUTOMU;: "Metabolic abnormalities in adult T- cell leukemia/lymphoma and induction of specific leukemic cell death using photodynamic therapy", SCIENTIFIC REPORTS, vol. 8, no. 1, 1 December 2018 (2018-12-01), pages 1 - 13, XP055758342, DOI: 10.1038/s41598-018-33175-7
DEMIAN VAN STRATEN; VIDA MASHAYEKHI; HENRIETTE DE BRUIJN; SABRINA OLIVEIRA; DOMINIC ROBINSON: "Oncologic Photodynamic Therapy: Basic Principles, Current Clinical Status and Future Directions", CANCERS, vol. 9, no. 2, 18 February 2017 (2017-02-18), pages 1 - 54, XP055387018, DOI: 10.3390/cancers9020019
T NAMIKAWA ET AL., WORLD J GASTROENTEROL, vol. 21, no. 29, 2015, pages 8769 - 8775
UEDA K ET AL., PROC NATL ACAD SCI USA, vol. 84, 1987, pages 3004 - 3008
TADA Y ET AL., INT J CANCER, vol. 98, 2002, pages 630 - 635
CASAS A ET AL., CURR MED CHEM, vol. 18, no. 16, 2011, pages 2486 - 515
LUKSIENE Z ET AL., MEDICINA (KAUNAS, vol. 39, no. 7, 2003, pages 677 - 82
LINGLING XU; ZHANG XUEQING; CHENG WENZHAO; WANG YONG; YI KAINING; WANG ZHILONG; ZHANG YILING; SHAO LINXIANG; ZHAO TIEJUN: "Hypericin-photodynamic therapy inhibits the growth of adult T- cell leukemia cells through induction of apoptosis and suppression of viral transcription", RETROVIROLOGY, vol. 16, 5, 19 February 2019 (2019-02-19), pages 1 - 13, XP055758340, DOI: 10.1186/s12977-019-0467-0
SIRINART CHIO-SRICHAN, OUDRHIRI NOUFISSA, BENNACEUR-GRISCELLI ANNELISE, TURHAN ALI G., DUMAS PAUL, REFREGIERS MATTHIEU: "Toxicity and phototoxicity of hypocrellin A on malignant human cell lines, evidence of a synergistic action of photodynamic therapy with Imatinib mesylate", JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B: BIOLOGY, vol. 99, no. 2, 2010306, pages 100 - 104, XP055759228, ISSN: 1011-1344, DOI: 10.1016/j.jphotobiol. 2010.03.001
TAKASHI OKA; MIZUNO HAJIME; SAKATA MASUMI; FUJITA HIROFUMI; YOSHINO TADASHI; YAMANO YOSHIHISA; UTSUMI KOZO; MASUJIMA TSUTOMU;: "Metabolic abnormalities in adult T- cell leukemia/lymphoma and induction of specific leukemic cell death using photodynamic therapy", SCIENTIFIC REPORTS, vol. 8, no. 1, 1 December 2018 (2018-12-01), pages 1 - 13, XP055758342, DOI: 10.1038/s41598-018-33175-7
DEMIAN VAN STRATEN; VIDA MASHAYEKHI; HENRIETTE DE BRUIJN; SABRINA OLIVEIRA; DOMINIC ROBINSON: "Oncologic Photodynamic Therapy: Basic Principles, Current Clinical Status and Future Directions", CANCERS, vol. 9, no. 2, 18 February 2017 (2017-02-18), pages 1 - 54, XP055387018, DOI: 10.3390/cancers9020019
T NAMIKAWA ET AL., WORLD J GASTROENTEROL, vol. 21, no. 29, 2015, pages 8769 - 8775
UEDA K ET AL., PROC NATL ACAD SCI USA, vol. 84, 1987, pages 3004 - 3008
TADA Y ET AL., INT J CANCER, vol. 98, 2002, pages 630 - 635
CASAS A ET AL., CURR MED CHEM, vol. 18, no. 16, 2011, pages 2486 - 515
LUKSIENE Z ET AL., MEDICINA (KAUNAS, vol. 39, no. 7, 2003, pages 677 - 82
Attorney, Agent or Firm:
YAMAO, Norihito et al. (JP)
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