PHARMACEUTICAL PREPARATION CONTAINING BEPOTASTINE AND GLYCERYL BEHENATE

WIPO Patent Application WO/2015/183047

A1

The present invention relates to a pharmaceutical composition containing bepotastine or a pharmaceutically acceptable salt thereof, and glyceryl behenate. The pharmaceutical preparation according to the present invention comprises an optically stable double-layer tablet preparation, which comprises: (a) a first layer containing bepotastine or a pharmaceutically acceptable salt thereof and having immediate-release characteristics; and (b) a second layer containing bepotastine or a pharmaceutically acceptable salt thereof and having sustained-release characteristics. The bepotastine sustained-release double-layer tablet preparation according to the present invention exhibits an excellent release pattern and bio-availability and has optically stability, and thus can be favorably used in the treatment of allergic rhinitis and pruritus.

KIM SOON-HOE (KR)
SON MI-WON (KR)
JANG SUN-WOO (KR)
WON DONG-HAN (KR)
CHOI MOON-YOUNG (KR)
HWANG HYUNG-DON (KR)
KIM HWAN-HO (KR)
KIM AH-YOUNG (KR)
KIM GOEN (KR)
KIM MIN-SOO (KR)
CHOO GWANG-HO (KR)
CHA KWANG-HO (KR)
KIM JEONG-SOO (KR)
KANG SEUNG-YEOB (KR)

PCT/KR2015/005439

December 03, 2015

May 29, 2015

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DONG A ST CO LTD (KR)

A61K9/24; A61K9/22; A61K31/4545

KR20140016260A	2014-02-07
KR20140052540A	2014-05-07
KR20110136074A	2011-12-21
KR20110026662A	2011-03-16
JP2006045134A	2006-02-16
KR20130135296A	2013-12-10

ROH, Jae-Chull (KR)
노재철 (KR)

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