PHOSPHODIESTERASE 10A7 ISOFORMS AND METHODS OF USE

Title:

PHOSPHODIESTERASE 10A7 ISOFORMS AND METHODS OF USE

Document Type and Number:

WIPO Patent Application WO2004090126

Kind Code:

A8

Abstract:

The invention relates to mammalian phosphodiesterase PDE10A7 isoforms, as well as the nucleic acids encoding such polypeptides. The invention further relates to methods for utilizing such polypeptides in diagnostic assays and in methods of screening potential modulators, especially inhibitors, of the novel PDE10A7 disclosed herein. The polypeptides of the invention are involved in many physiological processes including, e.g., the formation of memory, psychiatric disorders, and cognitive disorders.

Inventors:

WANG DAGUANG (US)
BUGAJ-GAWEDA BOZENA (US)

Application Number:

PCT/US2004/009878

Publication Date:

December 29, 2004

Filing Date:

March 30, 2004

Export Citation:

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Assignee:

MEMORY PHARM CORP (US)
WANG DAGUANG (US)
BUGAJ-GAWEDA BOZENA (US)

International Classes:

A01K67/027; C07K16/40; C12N5/10; C12N9/00; C12N9/16; (IPC1-7): C12N9/16; C07K16/40; C12N5/10; A01K67/027

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