PIPERAZINE DERIVATIVE - TAISHO PHARMACEUTICAL CO LTD

Title:

PIPERAZINE DERIVATIVE

Document Type and Number:

WIPO Patent Application WO/2003/053927

Kind Code:

A1

Abstract:

A piperazine derivative represented by the formula (1) [wherein n is an integer of 1 to 8&semi R¹ represents hydrogen or C₁₋₁₀ alkyl&semi A represents CH or nitrogen&semi Ar¹ represents phenyl or substituted phenyl&semi and Y represents a group represented by the formula Y¹−Y²−Ar² or Y³−Y⁴(Ar⁵)−Ar⁶] or a pharmaceutically acceptable salt of the derivative. The novel piperazine derivative has MC4 receptor antagonistic activity.

Inventors:

NAKAZATO ATSURO (JP)
ISHII TAKAAKI (JP)
NOZAWA DAI (JP)

Application Number:

PCT/JP2002/013317

Publication Date:

July 03, 2003

Filing Date:

December 19, 2002

Export Citation:

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Assignee:

TAISHO PHARMACEUTICAL CO LTD (JP)
NAKAZATO ATSURO (JP)
ISHII TAKAAKI (JP)
NOZAWA DAI (JP)

International Classes:

A61K31/496; A61K31/517; A61P3/04; A61P25/22; A61P25/24; A61P43/00; C07D209/48; C07D225/02; C07D231/12; C07D233/70; C07D233/84; C07D239/26; C07D239/96; C07D261/08; C07D263/32; C07D277/28; C07D277/34; C07D277/40; C07D277/56; C07D295/02; C07D295/13; C07D307/91; C07D311/90; C07D313/18; (IPC1-7): C07D209/48; C07D211/26; C07D231/12; C07D233/70; C07D233/84; C07D239/26; C07D239/42; C07D261/08; C07D263/32; C07D277/40; C07D277/56; C07D295/12; C07D295/14; C07D307/91; C07D313/18; A61K31/496; A61K31/517; A61P3/04; A61P25/22; A61P25/24; A61P43/00

Domestic Patent References:

WO2002000259A1	2002-01-03
WO1996005185A1	1996-02-22
WO2000035878A1	2000-06-22
WO1999055695A1	1999-11-04
WO1997028140A1	1997-08-07

Foreign References:

EP0310268A2	1989-04-05
EP0479546A2	1992-04-08

Other References: