Title:
POLYMER-MODIFIED MAGNETIC NANOMATERIAL, AND PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/274252
Kind Code:
A1
Abstract:
Disclosed in the present invention are a polymer-modified magnetic nanomaterial, and a preparation method therefor and the use thereof. Provided in the present invention is a method for preparing the polymer-modified magnetic nanomaterial. The method comprises the following steps: under an inert atmosphere and in the presence of plasma glow, heating a mixture of the polymer and a solvent to obtain an atomized form, and modifying the magnetic nanomaterial with same to obtain the polymer-modified magnetic nanomaterial. The polymer-modified magnetic nanomaterial provided in the present invention has a high polymer modification amount and a good stability, can be used in the enrichment and separation of a glycosylated protein, a polypeptide substance, a nucleic acid, a circulating tumor cell, an exosome, etc., has a fast response time, and can, for example, be used for the preparation of a drug or reagent for capturing the circulating tumor cell in body fluids, such as peripheral blood/urine.
Inventors:
CHEN BINGDI (CN)
LE WENJUN (CN)
CUI ZHENG (CN)
LE WENJUN (CN)
CUI ZHENG (CN)
Application Number:
PCT/CN2022/102012
Publication Date:
January 05, 2023
Filing Date:
June 28, 2022
Export Citation:
Assignee:
UNIV TONGJI (CN)
International Classes:
B01J20/26
Foreign References:
| CN107519501A | 2017-12-29 | |||
| CN106552600A | 2017-04-05 | |||
| US20100190006A1 | 2010-07-29 |
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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