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Title:
POSITIVE ALLOSTERIC MODULATORS OF THE NICOTINIC ACETYLCHOLINE RECEPTOR
Document Type and Number:
WIPO Patent Application WO2003093250
Kind Code:
A3
Abstract:
The invention provides compounds of Formula I: (1) these compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful in pharmaceuticals used to treat diseases or conditions in which alpha7 nAChR is known to be involved.

Inventors:
PIOTROWSKI DAVID W (US)
ROGERS BRUCE N (US)
MCWHORTER WILLIAM W JR (US)
WALKER DANIEL P (US)
CORBETT JEFFREY W (US)
GROPPI VINCENT E JR (US)
RUDMANN DANIEL G (US)
Application Number:
US0311493W
Publication Date:
December 23, 2004
Filing Date:
April 28, 2003
Export Citation:
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Assignee:
UPJOHN CO (US)
PIOTROWSKI DAVID W (US)
ROGERS BRUCE N (US)
MCWHORTER WILLIAM W JR (US)
WALKER DANIEL P (US)
CORBETT JEFFREY W (US)
GROPPI VINCENT E JR (US)
RUDMANN DANIEL G (US)
International Classes:
C07C275/34; C07C275/40; C07C323/44; C07C335/18; C07D213/75; C07D231/16; C07D231/40; C07D233/88; C07D261/14; C07D277/48; C07D277/56; C07D277/82; C07D285/135; C07D413/12; C07D417/12; C07D285/12; (IPC1-7): C07C275/34; C07D261/14; C07D285/12; C07D417/12; C07D277/48; C07D233/88; C07D413/12; C07C275/40; C07C335/18; A61K31/395; A61K31/17
Domestic Patent References:
WO2002002071A22002-01-10
WO2000026203A12000-05-11
WO1994022807A11994-10-13
WO1999000357A11999-01-07
WO1997045400A11997-12-04
WO2001068568A22001-09-20
WO1996025157A11996-08-22
WO2000035455A12000-06-22
WO2002020016A12002-03-14
Foreign References:
DE2436179A11975-02-06
US5814646A1998-09-29
US3990879A1976-11-09
US5162360A1992-11-10
US5059614A1991-10-22
Other References:
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