Title:
PREPARATION METHOD FOR MULBERRY SILK THAT FLUORESCES UNDER NEAR-INFRARED LIGHT AND PRODUCT
Document Type and Number:
WIPO Patent Application WO/2020/259490
Kind Code:
A1
Abstract:
Disclosed is a preparation method for mulberry silk that fluoresces under near-infrared light, comprising: (1) preparing upconversion nanoparticles, and performing surface modification with concanavalin to obtain modified upconversion nanoparticles; (2) uniformly dispersing the modified upconversion nanoparticles in water to formulate an aqueous solution of the upconversion nanoparticles; (3) picking mature mulberry leaves, immersing the mulberry leaves in the aqueous solution system of the nanoparticles, leaching water, and naturally drying the mulberry leaves; (4) after silkworms have grown for a set time, feeding the treated mulberry leaves to the silkworms until the silkworms spin silk cocoons; and (5) collecting the silk, so as to obtain mulberry silk that fluoresces under near-infrared light. The present invention selects upconversion nanoparticles capable of emitting fluorescence under the irradiation of near-infrared light which has stronger penetration, thus has better application in deep tissue imaging. Furthermore, the upconversion nanoparticles have more stable properties, higher biological safety, stronger signal-to-noise ratio, and a wider application range.
Inventors:
YANG MINGYING (CN)
WANG JIE (CN)
CHEN YUYIN (CN)
ZHANG YING (CN)
WANG JIE (CN)
CHEN YUYIN (CN)
ZHANG YING (CN)
Application Number:
PCT/CN2020/097679
Publication Date:
December 30, 2020
Filing Date:
June 23, 2020
Export Citation:
Assignee:
UNIV ZHEJIANG (CN)
International Classes:
A01K67/04; A23K50/90; C09K11/02
Foreign References:
| CN110367209A | 2019-10-25 | |||
| CN102677182A | 2012-09-19 | |||
| CN109588375A | 2019-04-09 | |||
| CN107446581A | 2017-12-08 | |||
| CN107558187A | 2018-01-09 | |||
| KR20090046616A | 2009-05-11 | |||
| JP2003088274A | 2003-03-25 |
Attorney, Agent or Firm:
HANGZHOU ZHIXIAN PATENT AGENCY (CN)
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