Title:
PRO-THROMBIN PURIFICATION
Document Type and Number:
WIPO Patent Application WO/2021/108976
Kind Code:
A1
Abstract:
Provided is a method of purifying a protein of interest from a medium comprised of adsorbent and the protein. The method includes, inter alia, providing the medium of the protein, which is at least partially adsorbed into/onto the adsorbent, and performing pressure filtering to wash the adsorbent-adsorbed protein and/or to elute the protein from the adsorbent, thereby at least partially purifying the protein.
Inventors:
YU AIBIN (CN)
YU JIANPING (CN)
NUR ISRAEL (IL)
WEISSMAN LIOR (IL)
PODOLER ITAI (IL)
YU JIANPING (CN)
NUR ISRAEL (IL)
WEISSMAN LIOR (IL)
PODOLER ITAI (IL)
Application Number:
PCT/CN2019/122619
Publication Date:
June 10, 2021
Filing Date:
December 03, 2019
Export Citation:
Assignee:
OMRIX BIOPHARMACEUTICALS LTD (IL)
GUANGZHOU BIOSEAL BIOTECH CO LTD (CN)
GUANGZHOU BIOSEAL BIOTECH CO LTD (CN)
International Classes:
C12Q1/56; C12N9/74; G01N33/48
Domestic Patent References:
| WO2016123804A1 | 2016-08-11 |
Foreign References:
| CN105950576A | 2016-09-21 | |||
| CN105985940A | 2016-10-05 | |||
| US20050265989A1 | 2005-12-01 |
Other References:
JOBIN F., ESNOUF M. P.: "Studies on the formation of the prothrombin-converting complex", BIOCHEMICAL JOURNAL, BIOCHEMICAL SOCIETY, LONDON, GB, vol. 102, no. 3, 1 March 1967 (1967-03-01), GB, pages 666 - 674, XP055819438, ISSN: 0006-2936, DOI: 10.1042/bj1020666
GANROT, P.O. ; KINDMARK, C.O.: "A simple two-step procedure for isolation of C-reactive protein", BBA - PROTEIN STRUCTURE., ELSEVIER SCIENCE BV, AMSTERDAM., NL, vol. 194, no. 2, 23 December 1969 (1969-12-23), NL, pages 443 - 448, XP023515202, ISSN: 0005-2795, DOI: 10.1016/0005-2795(69)90104-4
GANROT, P.O. ; KINDMARK, C.O.: "A simple two-step procedure for isolation of C-reactive protein", BBA - PROTEIN STRUCTURE., ELSEVIER SCIENCE BV, AMSTERDAM., NL, vol. 194, no. 2, 23 December 1969 (1969-12-23), NL, pages 443 - 448, XP023515202, ISSN: 0005-2795, DOI: 10.1016/0005-2795(69)90104-4
Attorney, Agent or Firm:
CHINA PATENT AGENT (H.K.) LTD. (CN)
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