Title:
PROBIOTIC COMPOSITIONS FOR TREATING AND PREVENTING COLORECTAL CANCER
Document Type and Number:
WIPO Patent Application WO/2023/011591
Kind Code:
A1
Abstract:
Provided are compositions and methods for treating colorectal cancer or for reducing the risk of developing the disease in an individual.
Inventors:
YU JUN (CN)
WU KA KEI (CN)
LI QING (CN)
WU KA KEI (CN)
LI QING (CN)
Application Number:
PCT/CN2022/110285
Publication Date:
February 09, 2023
Filing Date:
August 04, 2022
Export Citation:
Assignee:
UNIV HONG KONG CHINESE (CN)
International Classes:
A61K35/74; A61P35/00
Foreign References:
| CN114558007A | 2022-05-31 | |||
| US20210023145A1 | 2021-01-28 | |||
| JP2020164493A | 2020-10-08 | |||
| EP0415470A2 | 1991-03-06 | |||
| EP3646857A1 | 2020-05-06 | |||
| CN109310719A | 2019-02-05 | |||
| CN104546944A | 2015-04-29 |
Other References:
SUGIMURA NAOKI, LI QING, CHU EAGLE SIU HONG, LAU HARRY CHEUK HAY, FONG WINNIE, LIU WEIXIN, LIANG CONG, NAKATSU GEICHO, SU ANTHONY : "Lactobacillus gallinarum modulates the gut microbiota and produces anti-cancer metabolites to protect against colorectal tumourigenesis", GUT MICROBIOTA, BRITISH MEDICAL ASSOCIATION , LONDON, UK, vol. 71, no. 10, 1 October 2022 (2022-10-01), UK , pages 2011 - 2021, XP093032007, ISSN: 0017-5749, DOI: 10.1136/gutjnl-2020-323951
PLAVEC TINA VIDA, MITROVIĆ ANA, PERIŠIĆ NANUT MILICA, ŠTRUKELJ BORUT, KOS JANKO, BERLEC ALEŠ: "Targeting of fluorescent Lactococcus lactis to colorectal cancer cells through surface display of tumour‐antigen binding proteins", MICROBIAL BIOTECHNOLOGY, WILEY-BLACKWELL PUBLISHING LTD., GB, vol. 14, no. 5, 1 September 2021 (2021-09-01), GB , pages 2227 - 2240, XP093032009, ISSN: 1751-7915, DOI: 10.1111/1751-7915.13907
GAO CHUNXU, GANESH BHANU PRIYA, SHI ZHONGCHENG, SHAH RAJESH RASIK, FULTZ ROBERT, MAJOR ANGELA, VENABLE SUSAN, LUGO MONICA, HOCH KA: "Gut Microbe–Mediated Suppression of Inflammation-Associated Colon Carcinogenesis by Luminal Histamine Production", THE AMERICAN JOURNAL OF PATHOLOGY, ELSEVIER INC., US, vol. 187, no. 10, 1 October 2017 (2017-10-01), US , pages 2323 - 2336, XP093032014, ISSN: 0002-9440, DOI: 10.1016/j.ajpath.2017.06.011
CHUANG HUI-YU, JIANG JENG-KAE, YANG MUH-HWA, WANG HSEI-WEI, LI MING-CHUN, TSAI CHAN-YEN, JHANG YAU-YUN, HUANG JASON C.: "Aminopeptidase A initiates tumorigenesis and enhances tumor cell stemness via TWIST1 upregulation in colorectal cancer", ONCOTARGET, vol. 8, no. 13, 28 March 2017 (2017-03-28), pages 21266 - 21280, XP093032017, DOI: 10.18632/oncotarget.15072
PLAVEC TINA VIDA, MITROVIĆ ANA, PERIŠIĆ NANUT MILICA, ŠTRUKELJ BORUT, KOS JANKO, BERLEC ALEŠ: "Targeting of fluorescent Lactococcus lactis to colorectal cancer cells through surface display of tumour‐antigen binding proteins", MICROBIAL BIOTECHNOLOGY, WILEY-BLACKWELL PUBLISHING LTD., GB, vol. 14, no. 5, 1 September 2021 (2021-09-01), GB , pages 2227 - 2240, XP093032009, ISSN: 1751-7915, DOI: 10.1111/1751-7915.13907
GAO CHUNXU, GANESH BHANU PRIYA, SHI ZHONGCHENG, SHAH RAJESH RASIK, FULTZ ROBERT, MAJOR ANGELA, VENABLE SUSAN, LUGO MONICA, HOCH KA: "Gut Microbe–Mediated Suppression of Inflammation-Associated Colon Carcinogenesis by Luminal Histamine Production", THE AMERICAN JOURNAL OF PATHOLOGY, ELSEVIER INC., US, vol. 187, no. 10, 1 October 2017 (2017-10-01), US , pages 2323 - 2336, XP093032014, ISSN: 0002-9440, DOI: 10.1016/j.ajpath.2017.06.011
CHUANG HUI-YU, JIANG JENG-KAE, YANG MUH-HWA, WANG HSEI-WEI, LI MING-CHUN, TSAI CHAN-YEN, JHANG YAU-YUN, HUANG JASON C.: "Aminopeptidase A initiates tumorigenesis and enhances tumor cell stemness via TWIST1 upregulation in colorectal cancer", ONCOTARGET, vol. 8, no. 13, 28 March 2017 (2017-03-28), pages 21266 - 21280, XP093032017, DOI: 10.18632/oncotarget.15072
Attorney, Agent or Firm:
INSIGHT INTELLECTUAL PROPERTY LIMITED (CN)
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