Title:
PROBIOTICS COMPLEX COMPOSITION HAVING IMMUNOMODULATORY AND IMMUNE HOMEOSTASIS FUNCTIONS
Document Type and Number:
WIPO Patent Application WO/2023/229104
Kind Code:
A1
Abstract:
The present application relates to a mixed strain of probiotics having an immunomodulatory function and a composition comprising same. A composition comprising a mixed strain of probiotics having an immunomodulatory function as an active ingredient, according to an embodiment of the present application, has an immunomodulatory function by increasing the amount of NO production or suppressing excessive NO production induced by inflammatory substances, and thus, the strain can be applied to food compositions, health functional food compositions, pharmaceutical compositions, and the like.
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Inventors:
SOHN MINN (KR)
PARK JE SEONG (KR)
SHIN SO LIM (KR)
YOU YE JI (KR)
PARK JE SEONG (KR)
SHIN SO LIM (KR)
YOU YE JI (KR)
Application Number:
PCT/KR2022/012959
Publication Date:
November 30, 2023
Filing Date:
August 30, 2022
Export Citation:
Assignee:
LACTOMASON CO LTD (KR)
International Classes:
C12N1/20; A23L33/135; A61K35/747; A61P37/02; C12R1/225
Other References:
ANONYMOUS: "Nutrilite. Balance Within Immunity", AMWAY KOREA, 5 January 2021 (2021-01-05), XP093112207, Retrieved from the Internet [retrieved on 20231214]
KIM TAE-RAHK, CHOI KYOUNG-SOOK, JI YOSEP, HOLZAPFEL WILHELM H., JEON MIN-GYU: "Anti-inflammatory effects of Lactobacillus reuteri LM1071 via MAP kinase pathway in IL-1β-induced HT-29 cells", JOURNAL OF ANIMAL SCIENCE AND TECHNOLOGY, vol. 62, no. 6, 1 November 2020 (2020-11-01), pages 864 - 874, XP093046579, ISSN: 2672-0191, DOI: 10.5187/jast.2020.62.6.864
HWANG YONGPI: "N-32 Inhibitory Effects of Lactobacillus plantarum LM1001 on Particulate Matter-Induced Liver Injury", 46TH ANNUAL MEETING & INTERNATIONAL SYMPOSIUM. 2019, THE KOREAN SOCIETY FOR MICROBIOLOGY AND BIOTECHNOLOG, 1 January 2019 (2019-01-01), pages 586, XP093112200
KIM IN SUM, SUNG HAK KIM, JEONG A KIM, DA YOON YU, GWANG IL KIM, DONG-CHAN PARK, JONG MIN LIM, SANG SUK LEE, IN SOON CHOI, KWANG K: "IMMUNOMODULATORY EFFECTS OF Β-1: "3/1", 6-GLUCAN AND LACTOBACILLUS PLANTARUM LM1004 ON ATOPIC DERMATITIS MODELS", JOURNAL OF LIFE SCIENCE, KOREAN SOCIETY OF LIFE SCIENCE, KR, vol. 28, no. 1, 1 January 2018 (2018-01-01), KR , pages 17 - 25, XP093112203, ISSN: 1225-9918, DOI: 10.5352/JLS.2018.28.1.17
MATSUGUCHI TETSUYA, TAKAGI AKIMITSU, MATSUZAKI TAKESHI, NAGAOKA MASATO, ISHIKAWA KIMIKA, YOKOKURA TERUO, YOSHIKAI YASUNOBU: "Lipoteichoic Acids from Lactobacillus Strains Elicit Strong Tumor Necrosis Factor Alpha-Inducing Activities in Macrophages through Toll-Like Receptor 2", CLINICAL AND VACCINE IMMUNOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, vol. 10, no. 2, 1 March 2003 (2003-03-01), pages 259 - 266, XP093112204, ISSN: 1556-6811, DOI: 10.1128/CDLI.10.2.259-266.2003
KIM TAE-RAHK, CHOI KYOUNG-SOOK, JI YOSEP, HOLZAPFEL WILHELM H., JEON MIN-GYU: "Anti-inflammatory effects of Lactobacillus reuteri LM1071 via MAP kinase pathway in IL-1β-induced HT-29 cells", JOURNAL OF ANIMAL SCIENCE AND TECHNOLOGY, vol. 62, no. 6, 1 November 2020 (2020-11-01), pages 864 - 874, XP093046579, ISSN: 2672-0191, DOI: 10.5187/jast.2020.62.6.864
HWANG YONGPI: "N-32 Inhibitory Effects of Lactobacillus plantarum LM1001 on Particulate Matter-Induced Liver Injury", 46TH ANNUAL MEETING & INTERNATIONAL SYMPOSIUM. 2019, THE KOREAN SOCIETY FOR MICROBIOLOGY AND BIOTECHNOLOG, 1 January 2019 (2019-01-01), pages 586, XP093112200
KIM IN SUM, SUNG HAK KIM, JEONG A KIM, DA YOON YU, GWANG IL KIM, DONG-CHAN PARK, JONG MIN LIM, SANG SUK LEE, IN SOON CHOI, KWANG K: "IMMUNOMODULATORY EFFECTS OF Β-1: "3/1", 6-GLUCAN AND LACTOBACILLUS PLANTARUM LM1004 ON ATOPIC DERMATITIS MODELS", JOURNAL OF LIFE SCIENCE, KOREAN SOCIETY OF LIFE SCIENCE, KR, vol. 28, no. 1, 1 January 2018 (2018-01-01), KR , pages 17 - 25, XP093112203, ISSN: 1225-9918, DOI: 10.5352/JLS.2018.28.1.17
MATSUGUCHI TETSUYA, TAKAGI AKIMITSU, MATSUZAKI TAKESHI, NAGAOKA MASATO, ISHIKAWA KIMIKA, YOKOKURA TERUO, YOSHIKAI YASUNOBU: "Lipoteichoic Acids from Lactobacillus Strains Elicit Strong Tumor Necrosis Factor Alpha-Inducing Activities in Macrophages through Toll-Like Receptor 2", CLINICAL AND VACCINE IMMUNOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, vol. 10, no. 2, 1 March 2003 (2003-03-01), pages 259 - 266, XP093112204, ISSN: 1556-6811, DOI: 10.1128/CDLI.10.2.259-266.2003
Attorney, Agent or Firm:
MAPS INTELLECTUAL PROPERTY LAW FIRM (KR)
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