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Title:
A PROCESS FOR MAKING ESTRA-4,9(10)-DIENE STEROIDS
Document Type and Number:
WIPO Patent Application WO2002101014
Kind Code:
A3
Abstract:
A novel process for making estra-4,9(10)-diene-3,17-dione steroids from readily available 19-nor-androst-4-ene-3-one steroids by a straightforward three-step process. Products of this process are important intermediates in the preparation of biologically active substances.

Inventors:
VAN RHEENEN VERLAN H
HESSLER EDWARD J
Application Number:
PCT/US2002/018305
Publication Date:
March 25, 2004
Filing Date:
June 07, 2002
Export Citation:
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Assignee:
BRIDGE ORGANICS CO (US)
International Classes:
C07J1/00; C07J71/00; (IPC1-7): C07J71/00; C07J53/00
Foreign References:
US3211719A1965-10-12
US5516922A1996-05-14
DE3438484A11986-04-17
US5563131A1996-10-08
Other References:
DATABASE CAPLUS [online] HANSON ET AL.: "Synthesis, receptor binding and tissue distribution of 17.alpha.-E(1265I)iodovinyl-11.beta.-ethylestradiol", XP002965581, accession no. ACS Database accession no. 1993:486314
DATABASE CAPLUS [online] GARDI ET AL.: "Aromatization of 5,10-disubstituted 3-oxo-19-nor steroids and the analogous 10-hydroxy DELTA 4-derivatives", XP002965582, accession no. ACS Database accession no. 1964:52915
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