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Title:
A PROCESS FOR MANUFACTURE OF FOSINOPRIL SODIUM
Document Type and Number:
WIPO Patent Application WO2002088149
Kind Code:
A3
Abstract:
The present invention discloses a process for the synthesis of fosinopril as a single desired isomer of high purity in two steps comprising of (a) preparation of fosinopril as a mixture of four diastereomers and (b) separation of the desired isomer from the mixture through formation of alkali metal salts followed by crystallisation.

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Inventors:
DUBEY SUSHIL KUMAR (IN)
LAHIRI SASWATA (IN)
SINGH ANIL VIR (IN)
Application Number:
PCT/IN2001/000144
Publication Date:
June 05, 2003
Filing Date:
August 17, 2001
Export Citation:
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Assignee:
LUPIN LAB LTD (IN)
DUBEY SUSHIL KUMAR (IN)
LAHIRI SASWATA (IN)
SINGH ANIL VIR (IN)
International Classes:
C07B61/00; C07B57/00; C07F9/572; (IPC1-7): C07F9/572
Foreign References:
US4337201A1982-06-29
EP0437799A11991-07-24
GB2210370A1989-06-07
EP0442378A11991-08-21
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