Title:
A PROCESS FOR PREPARING OPTICAL PURE MILNACIPRAN AND ITS PHARMACEUTICALLY ACCEPTED SALTS
Document Type and Number:
WIPO Patent Application WO/2008/067752
Kind Code:
A1
Abstract:
Disclosed is a process for preparing of optical pure milnacipran and its pharmaceutically accepted
salts, wherein racemic milnacipran is used as raw material and the resolution is
carried out with tartaric acid derivatives or their compositions as resolving agents.
Inventors:
AI LIN (CN)
LIU XIAO (CN)
LIU XIAO (CN)
Application Number:
PCT/CN2007/071142
Publication Date:
June 12, 2008
Filing Date:
November 28, 2007
Export Citation:
Assignee:
AI LIN (CN)
International Classes:
C07C221/00; A61K31/16; A61P25/24; C07C225/18
Domestic Patent References:
| WO2006080555A1 | 2006-08-03 |
Foreign References:
| CN1699332A | 2005-11-23 | |||
| US20040162334A1 | 2004-08-19 | |||
| US20060014837A1 | 2006-01-19 | |||
| CN1699332A | 2005-11-23 |
Other References:
See also references of EP 2123628A4
BONNAUD ET AL., JOURNAL OF CHROMATOGRAPHY, vol. 318, 1985, pages 398 - 403
SHUTO ET AL., TETRAHEDRON LETTERS, vol. 37, 1996, pages 641 - 644
GRARD ET AL., ELECTROPHORESIS, vol. 21, 2000, pages 3028 - 3034
DOYLE; HU, ADVANCED SYNTHESIS AND CATALYSIS, vol. 343, 2001, pages 299 - 302
BONNAUD ET AL., JOURNAL OF CHROMATOGRAPHY, vol. 318, 1985, pages 398 - 403
SHUTO ET AL., TETRAHEDRON LETTERS, vol. 37, 1996, pages 641 - 644
GRARD ET AL., ELECTROPHORESIS, vol. 21, 2000, pages 3028 - 3034
DOYLE; HU, ADVANCED SYNTHESIS AND CATALYSIS, vol. 343, 2001, pages 299 - 302
Attorney, Agent or Firm:
CHENGDU JIUDINGTIANYUAN INTELLECTUAL PROPERTY AGENCY LTD. (Human Art Wisdom Plaza 33 Ximianqiao Street, Wuhou district, Chengdu Sichuan 1, CN)
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