Title:
PROCESS FOR PRODUCING 5−&lpar 3−CYANOPHENYL&rpar −3−FORMYLBENZOIC ACID COMPOUND
Document Type and Number:
WIPO Patent Application WO/2003/048111
Kind Code:
A1
Abstract:
A 5−(3−cyanophenyl)−3−formylbenzoic acid compound represented by the general formula (IV) is obtained by reacting a 5−bromo−3−hydroxymethylbenzoic acid compound represented by the general formula (I) with manganese dioxide to prepare a 5−bromo−3−formylbenzoic acid compound represented by the general formula (II) and reacting the compound represented by the formula (II) with 3−cyanophenylboric acid represented by the formula (III) in the presence of a palladium complex. (IV) (I) (II) (III) (In the formulae, R is hydrogen or C1−10 alkyl.)
Inventors:
TABE MASAYASU (JP)
MINOSHIMA TORU (JP)
MINOSHIMA TORU (JP)
Application Number:
PCT/JP2001/010521
Publication Date:
June 12, 2003
Filing Date:
November 30, 2001
Export Citation:
Assignee:
TEIJIN LTD (JP)
TABE MASAYASU (JP)
MINOSHIMA TORU (JP)
TABE MASAYASU (JP)
MINOSHIMA TORU (JP)
International Classes:
C07C51/353; C07C51/373; C07C67/31; C07C69/76; C07C253/30; C07C255/57; C07F5/02; (IPC1-7): C07C253/30; C07C67/31; C07C69/76; C07C255/57; C07F5/02
Domestic Patent References:
WO2000069811A1 | 2000-11-23 |
Foreign References:
JP2000336090A | 2000-12-05 | |||
JP2001335555A | 2001-12-04 |
Other References:
See also references of EP 1460059A4
Attorney, Agent or Firm:
Ishida, Takashi (ISHIDA & ASSOCIATES Toranomon 37 Mori
Bldg., 5-1, Toranomon 3-chom, Minato-ku Tokyo, JP)
Download PDF:
Previous Patent: COMPOUNDS FOR TREATMENT OF INFLAMMATION, DIABETES AND RELATED DISORDERS
Next Patent: BACTERIAL ENZYME INHIBITORS
Next Patent: BACTERIAL ENZYME INHIBITORS