Title:
PROCESS FOR PRODUCING PAROXETINE SALT CONTAINING SUBSTANTIALLY NO ORGANIC SOLVENT
Document Type and Number:
WIPO Patent Application WO/2002/022609
Kind Code:
A1
Abstract:
A process for producing a paroxetine salt containing no organic solvents by substantially and safely removing the organic solvent contained in paroxetine hydrochloride. The process comprises neutralizing paroxetine hydrochloride containing an organic solvent to form paroxetine, subsequently forming a salt of paroxetine with an acid other than hydrochloric acid, and crystallizing the salt from an organic solvent to obtain the paroxetine salt, which is not a hydrochloride.
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Inventors:
WANG SHU-ZHONG (JP)
SAITO ERIKA (JP)
SHIMOKAWA NAOYA (JP)
SAITO ERIKA (JP)
SHIMOKAWA NAOYA (JP)
Application Number:
PCT/JP2001/007967
Publication Date:
March 21, 2002
Filing Date:
September 13, 2001
Export Citation:
Assignee:
ASAHI GLASS CO LTD (JP)
WANG SHU ZHONG (JP)
SAITO ERIKA (JP)
SHIMOKAWA NAOYA (JP)
WANG SHU ZHONG (JP)
SAITO ERIKA (JP)
SHIMOKAWA NAOYA (JP)
International Classes:
A61K31/4525; A61P25/16; A61P25/24; A61P43/00; C07D405/12; (IPC1-7): C07D405/12
Domestic Patent References:
WO2000039121A1 | 2000-07-06 | |||
WO1998056787A1 | 1998-12-17 | |||
WO1996024595A1 | 1996-08-15 |
Foreign References:
EP0810224A1 | 1997-12-03 |
Attorney, Agent or Firm:
Senmyo, Kenji (Kanda-Higashimatsushitacho Chiyoda-ku, Tokyo, JP)
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