Title:
PRODRUGS, PRODRUG COMPOSITIONS AND RELATED METHODS
Document Type and Number:
WIPO Patent Application WO/2024/020379
Kind Code:
A3
Abstract:
Prodrugs including cleavable moieties capable of specific binding to a target are presented. Related pharmaceutical compositions and methods are also presented.
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Inventors:
MAJUMDER PRADIP KUMAR (US)
AMAN AHMED MASUD (US)
DAKSHINAMURTHY PRAVIN KUMAR (US)
SHIRIN SALMA (US)
CHATTERJEE SOHANG (US)
AMAN AHMED MASUD (US)
DAKSHINAMURTHY PRAVIN KUMAR (US)
SHIRIN SALMA (US)
CHATTERJEE SOHANG (US)
Application Number:
PCT/US2023/070399
Publication Date:
March 14, 2024
Filing Date:
July 18, 2023
Export Citation:
Assignee:
PRAESIDIA BIOTHERAPEUTICS INC (US)
International Classes:
A61K31/4704; A61K31/395; A61K31/4741; A61K31/33
Domestic Patent References:
| WO2021212638A1 | 2021-10-28 | |||
| WO2022078524A2 | 2022-04-21 |
Foreign References:
| US20100286065A1 | 2010-11-11 |
Other References:
VENTEICHER BROOKLYNN, MERKLIN KASEY, NGO HUY X., CHIEN HUAN‐CHIEH, HUTCHINSON KEINO, CAMPBELL JEROME, WAY HANNAH, GRIFFITH JOSEPH,: "‐Type Amino Acid Transporter 1‐Targeted Cellular and Brain Uptake", CHEMMEDCHEM COMMUNICATIONS, WILEY-VCH, DE, vol. 16, no. 5, 3 March 2021 (2021-03-03), DE , pages 869 - 880, XP055890926, ISSN: 1860-7179, DOI: 10.1002/cmdc.202000824
KAKEYA NOBUHARU, NISHIMURA KENICHI, YOSHIMI AKIHISA, NAKAMURA SYOHEI, NISHIZAWA SUSUMU, TAMAKI SATOSHI, MATSUI HIROSHI, KAWAMURA : "Studies on Prodrugs of Cephalosporins. I. Synthesis and Biological Properties of Glycyloxybenzoyloxymethyl and Glycylaminobenzoyloxymethyl Esters of 7beta-[2-(2-Aminothiazol- 4-yl)-(Z)-2-methoxyiminoacetamido]-3-methyl-3-cephem-4-carboxylic Acid", CHEMICAL AND PHARMACEUTICAL BULLETIN, vol. 32, 1 January 1984 (1984-01-01), pages 692 - 698, XP093149491
KAKEYA NOBUHARU, NISHIMURA KENICHI, YOSHIMI AKIHISA, NAKAMURA SYOHEI, NISHIZAWA SUSUMU, TAMAKI SATOSHI, MATSUI HIROSHI, KAWAMURA : "Studies on Prodrugs of Cephalosporins. I. Synthesis and Biological Properties of Glycyloxybenzoyloxymethyl and Glycylaminobenzoyloxymethyl Esters of 7beta-[2-(2-Aminothiazol- 4-yl)-(Z)-2-methoxyiminoacetamido]-3-methyl-3-cephem-4-carboxylic Acid", CHEMICAL AND PHARMACEUTICAL BULLETIN, vol. 32, 1 January 1984 (1984-01-01), pages 692 - 698, XP093149491
Attorney, Agent or Firm:
REYNOLDS, Anne M. (US)
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