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Title:
PROGNOSIS EVALUATION METHOD FOR PANCREATIC CANCER
Document Type and Number:
WIPO Patent Application WO/2014/185466
Kind Code:
A1
Abstract:
Provided are a method for identifying markers useful in evaluating the prognosis of pancreatic cancer and for predicting the prognosis of pancreatic cancer using said markers, and a test kit for predicting the prognosis of pancreatic cancer using said markers. A method for evaluating the prognosis of pancreatic cancer which is characterized in that the expression level of EBI3 in a biological sample isolated from a pancreatic cancer patient is measured.

Inventors:
HIRAOKA NOBUYOSHI (JP)
ISHIKAWA YOSHINORI (JP)
YAMAZAKI RIE (JP)
Application Number:
PCT/JP2014/062875
Publication Date:
November 20, 2014
Filing Date:
May 14, 2014
Export Citation:
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Assignee:
NAT CANCER CT (JP)
International Classes:
C12Q1/68; C12N15/09; C12Q1/02; G01N33/574; C07K16/24
Foreign References:
JP2008260769A2008-10-30
Other References:
LONG, J. ET AL.: "IL -35 over-expression increases apoptosis sensitivity and suppresses cell growth in human cancer cells", BIOCHEM. BIOPHYS. RES. COMMUN., vol. 430, 2012, pages 364 - 369, XP028962882, doi:10.1016/j.bbrc.2012.11.004
LIU, L. ET AL.: "Effects on apoptosis and cell cycle arrest contribute to the antitumor responses of interleukin-27 mediated by retrovirus in human pancreatic carcinoma cells", ONCOL. REP., vol. 27, 2012, pages 1497 - 1503
TAKAMASA TAKAHASHI ET AL.: "TS1 Suigan 47 Shorei no Rinsho Byorigakuteki Tokucho Oyobi Yogo Inshi", JOURNAL OF JAPAN SURGICAL SOCIETY, vol. 112, no. 1ยท2, 2011, pages 873, PS-212 - 2
NISHINO, R. ET AL.: "Identification of Epstein- Barr virus-induced gene 3 as a novel serum and tissue biomarker and a therapeutic target for lung cancer", CLIN. CANCER RES., vol. 17, no. 19, 2011, pages 6272 - 6286
YATARO DAIGO: "Haigan Shokudogan no Seimei Yogo ni Kiyo suru Jitsuyoteki Byotai Shindan Biomarker no Kaihatsu Kenkyu", DAIWA SECURITIES HEALTH FOUNDATION HEISEI 22 NENDO (DAI 37 KAI) CHOSA KENKYU JOSEI KENKYU RONBUN, 2012, pages 87 - 89, Retrieved from the Internet [retrieved on 20140724]
RYOHEI NISHINO: "Epstein-Barr virus-induced gene 3 wa Haigan no Shinki Kessei Soshiki Biomarker Oyobi Chiryo Hyoteki Bunshi de aru", HIROSHIMA UNIVERSITY GAKUI RONBUN YOSHI, 2011, Retrieved from the Internet [retrieved on 20140724]
Attorney, Agent or Firm:
THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)
Patent business corporation Alga patent firm (JP)
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