Title:
PROGNOSTIC METHOD FOR ANTI-RESORPTIVE TREATMENT
Document Type and Number:
WIPO Patent Application WO2000022437
Kind Code:
A9
Abstract:
The present invention describes a new model based on the logistic combination of the percentage change of the level of a bone marker at a predetermined time period and the level of the bone marker at a baseline or at the predetermined period to predict shortly after initiating an anti-resorptive therapy those patients who will not significantly improve their bone BMD after two years of treatment or those patients who do not comply with therapy. In addition, the present invention also provides for the first time a defined cut-off value that can easily be used in clinical practice to identify individual non-responder or non-compliant patients after a short period of treatment, such as six months.
Inventors:
DARTE CLAUDE
Application Number:
PCT/US1999/020698
Publication Date:
October 05, 2000
Filing Date:
September 09, 1999
Export Citation:
Assignee:
HYBRITECH INC (US)
International Classes:
G01N33/50; C12Q1/42; G01N33/573; G01N33/68; (IPC1-7): G01N33/68; G01N33/573
Download PDF: