PROTEASE INHIBITORS - SMITHKLINE BEECHAM CORP

Title:

PROTEASE INHIBITORS

Document Type and Number:

WIPO Patent Application WO2001034599

Kind Code:

A9

Abstract:

This invention relates to the compound of Formula (I): or a pharmaceutically acceptable salt, hydrate or solvate thereof, which is an inhibitor of cysteine proteases, particularly cathepsin K, and is useful in the treatment of diseases in which inhibition of bone loss or of cartilage degradation is a factor.

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Inventors:

MARQUIS ROBERT W JR (US)
VEBER DANIEL FRANK (US)

Application Number:

PCT/US2000/030685

Publication Date:

May 10, 2002

Filing Date:

November 08, 2000

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Assignee:

SMITHKLINE BEECHAM CORP (US)
MARQUIS ROBERT W JR (US)
VEBER DANIEL FRANK (US)

International Classes:

A61K31/55; A61P1/02; A61P19/02; A61P19/08; A61P19/10; A61P29/00; A61P43/00; C07B57/00; C07D401/14; (IPC1-7): C07D413/00; A61K31/55

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