Title:
PROTEIN-ENRICHED THERMOPLASTICS
Document Type and Number:
WIPO Patent Application WO1995001998
Kind Code:
A3
Abstract:
Thermoplastics interdispersed with a variety of functional thermostable proteins and methods for their production are provided. To prepare the subject thermoplastics, a plastic material is contacted with a thermostable polypeptide and then subjected to the heating and molding/extrusion/casting process. The resultant thermoplastics comprise the thermostable polypeptide on the formed plastic surface and at a depth below the plastic surface. The thermostable polypeptides contained in the disclosed compositions retain functional properties or binding specificities through the heating and molding/extrusion/casting processes. Preferred thermostable polypeptides used in the disclosed compositions include silk-like protein polymers, particularly ProNectin TM F. The disclosed methods and compositions find use in many applications where plastics containing finctional thermostable proteins are desired, in particular, cell cultureware.
Inventors:
DONOFRIO DAVID A (US)
STEDRONSKY ERWIN R (US)
STEDRONSKY ERWIN R (US)
Application Number:
PCT/US1994/007776
Publication Date:
January 19, 1995
Filing Date:
July 08, 1994
Export Citation:
Assignee:
PROTEIN POLYMER TECHNOLOGIES (US)
DONOFRIO DAVID A (US)
STEDRONSKY ERWIN R (US)
DONOFRIO DAVID A (US)
STEDRONSKY ERWIN R (US)
International Classes:
A61L17/00; A61L29/04; C07K14/00; C07K14/435; C07K14/78; C07K17/08; C12N1/06; C12N5/00; C12N15/11; C12N15/62; C12N15/66; C12N15/70; C12N15/75; (IPC1-7): C07K17/00
Foreign References:
| US4617271A | 1986-10-14 | |||
| JPS57108010A | 1982-07-05 |
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