Title:
PYRAZOLOPYRIDINE DERIVATIVE AND APPLICATION THEREOF IN MEDICINE
Document Type and Number:
WIPO Patent Application WO/2023/155866
Kind Code:
A1
Abstract:
The present invention relates to the compound shown in general formula (I) or to a stereoisomer, tautomer, deuterated substance, solvate, prodrug, metabolite, pharmaceutically-acceptable salt or eutectic crystal thereof, and to an intermediate and a preparation method thereof, and also to an application thereof in the preparation of a medicine for treating diseases related to USP1 activity or expression.
Inventors:
ZHANG CHEN (CN)
WANG JIANMIN (CN)
QIAN GUOFEI (CN)
YU YAN (CN)
TANG PINGMING (CN)
CHEN TENGFEI (CN)
LI YAO (CN)
YAN PANGKE (CN)
WANG JIANMIN (CN)
QIAN GUOFEI (CN)
YU YAN (CN)
TANG PINGMING (CN)
CHEN TENGFEI (CN)
LI YAO (CN)
YAN PANGKE (CN)
Application Number:
PCT/CN2023/076700
Publication Date:
August 24, 2023
Filing Date:
February 17, 2023
Export Citation:
Assignee:
SICHUAN HAISCO PHARMACEUTICAL CO LTD (CN)
International Classes:
A61K31/437; A61K31/395; A61K31/435; A61K31/4353; A61K31/438; A61P35/00; C07D401/02; C07D401/14; C07D471/02; C07D471/04; C07D471/12; C07D471/22; C07D487/04; C07D487/12; C07D487/22
Domestic Patent References:
| WO2013095761A1 | 2013-06-27 | |||
| WO2015051713A1 | 2015-04-16 |
Foreign References:
| CN113164485A | 2021-07-23 | |||
| CN108948002A | 2018-12-07 | |||
| CN109232358A | 2019-01-18 | |||
| CN109311843A | 2019-02-05 | |||
| CN113387931A | 2021-09-14 | |||
| EP2298731A1 | 2011-03-23 | |||
| US20120165305A1 | 2012-06-28 |
Attorney, Agent or Firm:
WU , FENG & ZHANG (CN)
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