Title:
PYRAZOLOPYRIDINONE COMPOUNDS
Document Type and Number:
WIPO Patent Application WO/2019/101182
Kind Code:
A1
Abstract:
Pyrazolopyridinone compounds, the pharmaceutical compositions comprising said compounds, and the use of said compounds as FGFR (fibroblast growth factor receptor) inhibitors and their use in the treatment of diseases, e.g. cancer.
Inventors:
GUO HAIBING (CN)
WAN ZHAO-KUI (CN)
QIN LUOHENG (CN)
LIU QIAN (CN)
CHEUNG WING SHUN (CN)
WAN ZHAO-KUI (CN)
QIN LUOHENG (CN)
LIU QIAN (CN)
CHEUNG WING SHUN (CN)
Application Number:
PCT/CN2018/117295
Publication Date:
May 31, 2019
Filing Date:
November 23, 2018
Export Citation:
Assignee:
JANSSEN PHARMACEUTICA NV (BE)
JOHNSON & JOHNSON CHINA INVEST LTD (CN)
JOHNSON & JOHNSON CHINA INVEST LTD (CN)
International Classes:
A61K31/437; C07D471/04; A61P35/00; C07D519/00
Domestic Patent References:
| WO2002018383A2 | 2002-03-07 | |||
| WO2004018419A2 | 2004-03-04 |
Other References:
FRAZIER, K. ET AL.: "Design and structure-activity relationship of heterocyclic analogs of 4- amino-3-benzimidazol-2-ylhydroquinolin-2-ones as inhibitors of receptor tyrosine kinases", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 16, no. 8, 30 January 2006 (2006-01-30), pages 2247 - 2251, XP025106948, ISSN: 0960-894X, DOI: doi:10.1016/j.bmcl.2006.01.020
Attorney, Agent or Firm:
NTD UNIVATION INTELLECTUAL PROPERTY AGENCY LTD. (CN)
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