PYRIDINE-CONTAINING POLYCYCLIC DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF

WIPO Patent Application WO/2023/134764

A1

The present invention relates to a pyridine-containing polycyclic derivative, and a preparation method therefor and the use thereof. In particular, the present invention relates to a compound as represented by general formula (I), a preparation method therefor, a pharmaceutical composition containing the compound, and the use thereof as a biological regulator in the preparation of a drug for treating autoimmune diseases, chronic inflammatory diseases, acute inflammatory diseases, autoinflammatory diseases, atherosclerosis, diabetes, fibrotic diseases, metabolic diseases, cancers, tumors, leukemia and lymphoma, wherein the definition of each substituent in general formula (I) is the same as that in the description.

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DONG JIAQIANG (CN)
DENG XINXIAN (CN)
YU WENSHENG (CN)
JIN FANGFANG (CN)
GONG ZHEN (CN)

PCT/CN2023/072370

July 20, 2023

January 16, 2023

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SHANGHAI HANSOH BIOMEDICAL CO LTD (CN)
JIANGSU HANSOH PHARMACEUTICAL GROUP CO LTD (CN)

C07D213/64; A61K31/444; A61K31/497; A61K31/501; A61K31/513; A61P29/00; A61P35/00; C07D213/72; C07D401/14; C07D405/14; C07D409/14

WO2021022186A1	2021-02-04
WO2023283338A1	2023-01-12

GE CHENG & CO., LTD. (CN)

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