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Title:
PYRIDOCYCLOHEPTANE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/022434
Kind Code:
A1
Abstract:
The present application relates to a substituted pyridocycloheptane derivative, a preparation method therefor, and use of a pharmaceutical composition comprising the derivative or a deuterated derivative in medicine. In particular, the present application relates to a substituted pyridocycloheptane derivative represented by General Formula (I), a preparation method therefor, a pharmaceutically acceptable salt thereof, and use thereof as a CGRP receptor antagonist in the prevention and/or treatment of CGRP-related diseases, particularly in the field of migraine. The definition of each substituent in general formula (I) is the same as that in the specification.

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Inventors:
YING YONGCHENG (CN)
LI GUOCHUN (CN)
YUAN XIAOHUI (CN)
YU SHANGHAI (CN)
GU LIMING (CN)
LOU WANQIAO (CN)
Application Number:
PCT/CN2023/109537
Publication Date:
February 01, 2024
Filing Date:
July 27, 2023
Export Citation:
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Assignee:
BRISE PHARMACEUTICALS CO LTD (CN)
International Classes:
C07D471/20; C07D207/00; C07D223/00; C07D401/14
Foreign References:
CN102656159A2012-09-05
CN102066358A2011-05-18
CN113563309A2021-10-29
CN109535161A2019-03-29
CN113226379A2021-08-06
Attorney, Agent or Firm:
BEIJING TANGSONG IP FIRM (CN)
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