REAL-TIME AUTOMATIC FOCUSING SYSTEM FOR MICROSCOPE

WIPO Patent Application WO/2021/184169

A1

A real-time automatic focusing system for a microscope, comprising an infrared light source module, an offset lens light path module, a detection module, and a focusing control module. The infrared light source module is used for emitting parallel laser beams; the offset lens light path module expands the parallel laser beams emitted by the infrared light source module into divergent light, and irradiates a sample interface (11) by means of a microscope objective lens (10), so that laser diffraction spots irradiated on the sample interface (11) form comet-shaped aberration; the detection module modulates comet-shaped diffraction spots formed by reflection of the sample interface (11) into linear spots and obtains defocusing amount related information of the microscopic system under the current field of view by analyzing the linear spots; and the focusing control module iteratively controls the axial movement of the microscope objective lens (10) based on the obtained defocusing amount related information until the defocusing amount meets a set target.

WO/2013/161348	IMAGE PROCESSING PROGRAM AND IMAGE PROCESSING DEVICE
JP2001021330	SLIT DISC FOR CONFOCAL DEVICE AND CONFOCAL DEVICE AND PICTURE MEASURING METHOD FOR THE SAME DEVICE
JPH03191324	ANALYZING DEVICE

LI SIHONG (CN)
HUANG SHUQIANG (CN)
FU XIONGFEI (CN)
YU YUE (CN)
WEN HUI (CN)

PCT/CN2020/079547

September 23, 2021

March 16, 2020

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SHENZHEN INST OF ADV TECH CAS (CN)

G02B21/00; G02B7/28

WO2003077008A2

2003-09-18

CN104932092A	2015-09-23
CN110809113A	2020-02-18
CN108646396A	2018-10-12
CN102597841A	2012-07-18
CN107407791A	2017-11-28
CN105093479A	2015-11-25
JP2005062515A	2005-03-10

BEIJING CHENGHUI LAW FIRM (CN)

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