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Title:
ROCURONIUM PREPARATION WITH IMPROVED VASCULAR PAIN, METHOD FOR PRODUCING SAME, AND METHOD FOR SUPPRESSING AND RELIEVING VASCULAR PAIN USING SAME
Document Type and Number:
WIPO Patent Application WO/2015/001995
Kind Code:
A1
Abstract:
 Provided is a rocuronium preparation that makes it possible to suppress vascular pain. This rocuronium preparation is characterized by containing rocuronium and a buffer and having titratable acidity of 100 mEq or less. The buffer may be an acetate buffer, citrate buffer, formate buffer, tartrate buffer, phosphate buffer, glycine-hydrochloric acid buffer, citrate-phosphate buffer, or the like.

Inventors:
JINBO KEISUKE (JP)
ITSUJI YUTAKA (JP)
Application Number:
PCT/JP2014/066504
Publication Date:
January 08, 2015
Filing Date:
June 23, 2014
Export Citation:
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Assignee:
MARUISHI PHARMA (JP)
International Classes:
A61K31/568; A61K9/08; A61K47/02; A61K47/12; A61K47/18; A61K47/24; A61P21/02; A61P23/00
Domestic Patent References:
WO1999027914A11999-06-10
Foreign References:
JP2009515895A2009-04-16
JPH0753751B21995-06-07
Other References:
NEMA S;: "EXCIPIENTS AND THEIR USE IN INJECTABLE PRODUCTS", PDA J. PHARM. SCI. TECHNOL., vol. 51, no. 4, 1997, pages 166 - 171, XP002489282
BR. J. ANAESTH., vol. 79, 1997, pages 382 - 383, XP055311537
DRUG INTERVIEW FORM OF ESLAX INTRAVENOUS 25 MG/2.5 ML AND ESLAX INTRAVENOUS 50 MG/5.0 ML, October 2010 (2010-10-01)
BRITISH JOURNAL OF CLINICAL ANESTHESIA, vol. 66, 1991, pages 189 - 195
JOURNAL OF CLINICAL ANESTHESIA, vol. 19, 2007, pages 418 - 423
See also references of EP 3017817A4
Attorney, Agent or Firm:
IWATANI, Ryo (JP)
Tatsu Iwatani (JP)
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