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Title:
SCAFFOLDING MATERIAL FOR STEM CELL CULTURES AND STEM CELL CULTURE METHOD USING SAME
Document Type and Number:
WIPO Patent Application WO/2019/131982
Kind Code:
A1
Abstract:
A scaffolding material for stem cell cultures, including synthetic resin, having a 100ºC storage elasticity of 1.0 × 104–1.0 × 108 Pa, and a ratio between 25ºC storage elasticity and 100ºC storage elasticity ((25ºC storage elasticity)/(100ºC storage elasticity)) of 1.0 × 101–1.0 × 105. This scaffolding material for stem cell cultures provides suitable hydrophilic properties and strength, high fixation of stem cells after seeding, highly efficient cell proliferation, and excellent scratch resistance.

Inventors:
HANEDA SATOSHI (JP)
MANABE YURIKO (JP)
ISHII RYOMA (JP)
IGUCHI HIROKI (JP)
ARAI YUHEI (JP)
Application Number:
PCT/JP2018/048391
Publication Date:
July 04, 2019
Filing Date:
December 27, 2018
Export Citation:
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Assignee:
SEKISUI CHEMICAL CO LTD (JP)
International Classes:
C12M3/00; C08F8/28; C12N5/0735; C12N5/074
Foreign References:
JP2009273444A2009-11-26
JP2006314285A2006-11-24
JP2006314285A2006-11-24
JP2010158180A2010-07-22
JP2017023008A2017-02-02
Other References:
TOGAMI W. ET AL.: "Effects of water-holding capability of the PVF sponge on the adhesion and differentiation of rat bone marrow stem cell culture", JOURNAL OF BIOMEDICAL MATERIALS RESEARCH A, vol. 102, no. 1, 22 July 2013 (2013-07-22), pages 247 - 253, XP055623441
TOGAMI W. ET AL.: "Effects of the water-holding capability of polyvinyl formal sponges on osteogenic ability in in vivo experiments", JOURNAL OF BIOMEDICAL MATERIALS RESEARCH B: APPLIED BIOMATERIALS, vol. 103, no. 1, 13 May 2014 (2014-05-13), pages 188 - 194, XP055623444
MIYOSHI H. ET AL.: "Three-dimensional culture of mouse bone marrow cells within a porous polymer scaffold: effects of oxygen concentration and stromal layer on expansion of haematopoietic progenitor cells", JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, vol. 5, no. 2, 23 July 2010 (2010-07-23), pages 112 - 118, XP055623447
See also references of EP 3733835A4
Attorney, Agent or Firm:
MOEGI PATENT OFFICE (JP)
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