Title:
SCREENING AND TREATMENT METHODS FOR PREVENTION OF PRETERM DELIVERY
Document Type and Number:
WIPO Patent Application WO2004071427
Kind Code:
A3
Abstract:
Provided herein are methods, combinations, and kits for screening and treating a subject. In practicing the methods a sample, such as urine, blood, plasma, saliva, cervical fluid, vaginal fluid, or a tissue sample, is obtained from a subject; if the level of a marker, such as a fetal restricted antigen or estriol, is indicative of a risk of imminent or preterm delivery, a progestational agent is administered to the subject. By virtue of administration of the agent delivery can be delayed.
Inventors:
HICKOK DURLIN (US)
HUSSA ROBERT (US)
FISCHER-COLBRIE MARK (US)
ANDERSON EMORY V (US)
SENYEI ANDREW E (US)
HUSSA ROBERT (US)
FISCHER-COLBRIE MARK (US)
ANDERSON EMORY V (US)
SENYEI ANDREW E (US)
Application Number:
PCT/US2004/003428
Publication Date:
April 14, 2005
Filing Date:
February 06, 2004
Export Citation:
Assignee:
ADEZA BIOMEDICAL CORP (US)
HICKOK DURLIN (US)
HUSSA ROBERT (US)
FISCHER-COLBRIE MARK (US)
ANDERSON EMORY V (US)
SENYEI ANDREW E (US)
HICKOK DURLIN (US)
HUSSA ROBERT (US)
FISCHER-COLBRIE MARK (US)
ANDERSON EMORY V (US)
SENYEI ANDREW E (US)
International Classes:
A61K31/20; A61K31/57; A61P15/06; C07J1/00; G01N33/53; G01N33/543; G01N33/74; A61K; (IPC1-7): G01N33/53; C07J1/00; A61P15/06
Domestic Patent References:
| WO1994017405A1 | 1994-08-04 |
Other References:
MEIS PAUL J: "17 Alpha hydroxyprogesterone caproate prevents recurrent preterm birth.", AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, vol. 187, no. 6 Supplement, December 2002 (2002-12-01), & 23RD ANNUAL MEETING OF THE SOCIETY FOR MATERNAL-FETAL MEDICINE; SAN FRANCISCO, CA, USA; FEBRUARY 03-08, 2003, pages S54, XP009042584, ISSN: 0002-9378
DA FONSECA EDUARDO B ET AL: "Prophylactic administration of progesterone by vaginal suppository to reduce the incidence of spontaneous preterm birth in women at increased risk: A randomized placebo-controlled double-blind study.", AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, vol. 188, no. 2, February 2003 (2003-02-01), pages 419 - 424, XP002313320, ISSN: 0002-9378
NOBLOT G ET AL: "THE USE OF MICRONIZED PROGESTERONE IN THE TREATMENT OF MENACE OF PRETERM DELIVERY", EUROPEAN JOURNAL OF OBSTETRICS AND GYNECOLOGY AND REPRODUCTIVE BIOLOGY, vol. 40, no. 3, 1991, pages 203 - 210, XP009042564, ISSN: 0301-2115
KEIRSE M J N C: "PROGESTOGEN ADMINISTRATION IN PREGNANCY MAY PREVENT PRETERM DELIVERY", BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, vol. 97, no. 2, 1990, pages 149 - 154, XP009042565, ISSN: 0306-5456
BITTAR ROBERTO EDUARDO ET AL: "Cervical fetal fibronectin in patients at increased risk for preterm delivery", AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, vol. 175, no. 1, 1996, pages 178 - 181, XP009042583, ISSN: 0002-9378
DARNE J ET AL: "INCREASED SALIVA OESTRIOL TO PROGESTERONE RATIO BEFORE IDIOPATHIC PRETERM DELIVERY : A POSSIBLE PREDICTOR FOR PRETERM LABOR?", BRITISH MEDICAL JOURNAL, LONDON, GB, vol. 294, 31 January 1987 (1987-01-31), pages 270 - 272, XP000646592, ISSN: 0267-0623
DA FONSECA EDUARDO B ET AL: "Prophylactic administration of progesterone by vaginal suppository to reduce the incidence of spontaneous preterm birth in women at increased risk: A randomized placebo-controlled double-blind study.", AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, vol. 188, no. 2, February 2003 (2003-02-01), pages 419 - 424, XP002313320, ISSN: 0002-9378
NOBLOT G ET AL: "THE USE OF MICRONIZED PROGESTERONE IN THE TREATMENT OF MENACE OF PRETERM DELIVERY", EUROPEAN JOURNAL OF OBSTETRICS AND GYNECOLOGY AND REPRODUCTIVE BIOLOGY, vol. 40, no. 3, 1991, pages 203 - 210, XP009042564, ISSN: 0301-2115
KEIRSE M J N C: "PROGESTOGEN ADMINISTRATION IN PREGNANCY MAY PREVENT PRETERM DELIVERY", BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, vol. 97, no. 2, 1990, pages 149 - 154, XP009042565, ISSN: 0306-5456
BITTAR ROBERTO EDUARDO ET AL: "Cervical fetal fibronectin in patients at increased risk for preterm delivery", AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, vol. 175, no. 1, 1996, pages 178 - 181, XP009042583, ISSN: 0002-9378
DARNE J ET AL: "INCREASED SALIVA OESTRIOL TO PROGESTERONE RATIO BEFORE IDIOPATHIC PRETERM DELIVERY : A POSSIBLE PREDICTOR FOR PRETERM LABOR?", BRITISH MEDICAL JOURNAL, LONDON, GB, vol. 294, 31 January 1987 (1987-01-31), pages 270 - 272, XP000646592, ISSN: 0267-0623
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