Title:
SHORT SYNTHETIC PEPTIDE AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/101748
Kind Code:
A1
Abstract:
Provided is a synthetic peptide consisting of the amino acid sequence set forth as X1ITYX2RLKX3. Also provided is a pharmaceutical composition including the peptide and a pharmaceutically acceptable carrier. Further provided are methods of treating and/or preventing a disease or a condition related to dry eye syndrome, psoriasis vulgaris or multiple myeloma, by administering to a subject in need of such treatment a composition containing a therapeutically effective amount of synthetic peptides.
Inventors:
TSAO YEOU-PING (CN)
HO TSUNG-CHUAN (CN)
HO TSUNG-CHUAN (CN)
Application Number:
PCT/CN2016/109504
Publication Date:
June 22, 2017
Filing Date:
December 12, 2016
Export Citation:
Assignee:
TSAO YEOU-PING (CN)
HO TSUNG-CHUAN (CN)
HO TSUNG-CHUAN (CN)
International Classes:
A61P27/02; A61K38/03; C07K7/04
Domestic Patent References:
| WO2009114539A2 | 2009-09-17 |
Foreign References:
| CN104650186A | 2015-05-27 | |||
| US8062890B2 | 2011-11-22 | |||
| US20120135518A1 | 2012-05-31 | |||
| CN1263770C | 2006-07-12 | |||
| CN101511357A | 2009-08-19 |
Other References:
NOMIZU, M. ET AL.: "Identification of Cell Binding Sequences in Mouse Laminin yl Chain by Systematic Peptide Screening.", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 272, no. 51, 19 December 1997 (1997-12-19), XP002157600, DOI: doi:10.1074/jbc.272.51.32198
KURATOMI, Y. ET AL.: "Laminingammal chain peptide, C-16 (KAFDITYVRLKF), promotes migration, MMP-9 secretion, and pulmonary metastasis of B16-F10 mouse melanoma cells.", BRITISH JOURNAL OF CANCER., vol. 86, no. 7, 31 December 2002 (2002-12-31), pages 1169 - 1173, XP 002493148
See also references of EP 3389784A4
BARABINO ET AL., IVOS, vol. 46, no. 8, 2005, pages 2766 - 2771
DURSUN ET AL., INVEST OPHTHALMOL VIS SCI., vol. 43, 2002, pages 632 - 8
VAN DER FITS ET AL., J IMMUNOL., vol. 182, 2009, pages 5836 - 45
KURATOMI, Y. ET AL.: "Laminingammal chain peptide, C-16 (KAFDITYVRLKF), promotes migration, MMP-9 secretion, and pulmonary metastasis of B16-F10 mouse melanoma cells.", BRITISH JOURNAL OF CANCER., vol. 86, no. 7, 31 December 2002 (2002-12-31), pages 1169 - 1173, XP 002493148
See also references of EP 3389784A4
BARABINO ET AL., IVOS, vol. 46, no. 8, 2005, pages 2766 - 2771
DURSUN ET AL., INVEST OPHTHALMOL VIS SCI., vol. 43, 2002, pages 632 - 8
VAN DER FITS ET AL., J IMMUNOL., vol. 182, 2009, pages 5836 - 45
Attorney, Agent or Firm:
CHINA ZHENGHE INTELLECTUAL PROPERTY AGENCY (CN)
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