Title:
SIMMONDSIN PROCESSING METHODS AND PRODUCTS
Document Type and Number:
WIPO Patent Application WO2003017931
Kind Code:
A3
Abstract:
The invention provides a process for reducing odour, bitterness, astringency and pungency of a Simmondsins extract by dissolving the Simmondsins extract in a solvent if the Simmondsins extract is in a dry form, reacting the liquid Simmondsins extract with a carbonaceous adsorbent, such as activated carbon, to obtain a mixture, separating the adsorbent from the mixture to obtain a purified liquid extract, and drying the purified liquid extract. The invention also provides a process for preparing a Simmondsins extract having reduced odour, bitterness, astringency and pungency by eluting plant material containing Simmondsins with a polar organic solvent to dissolve the Simmondsins, separating the eluent containing the Simmondsins and the solvent from the plant material to obtain a dilute crude Simmondsins extract, concentrating the crude Simmondsins extract, removing any oils from the concentrated crude : Simmondsins extract, and then carrying out the steps for I reducing odour, bitterness, astringency and pungency of i extract as above. The invention also provides a feed .containing a Simmondsins extract having reduced odour, bitterness, astringency and pungency.
Inventors:
TANG QINQNONG
FU WENHUI
BROWN JAMES HOWARD
FU WENHUI
BROWN JAMES HOWARD
Application Number:
PCT/US2002/026554
Publication Date:
July 03, 2003
Filing Date:
August 21, 2002
Export Citation:
Assignee:
INT FLORA TECHNOLOGIES LTD (US)
International Classes:
A61K31/70; A61K36/185; C07H5/06; A61K; (IPC1-7): A61K35/78
Foreign References:
| US6007823A | 1999-12-28 | |||
| US4356197A | 1982-10-26 | |||
| US5650157A | 1997-07-22 | |||
| US5672371A | 1997-09-30 |
Other References:
VAN BOVEN ET AL.: "Extraction and liquid chromatographic method for the determination of simmondsin in plasma", J. CHROM. B: BIOMED. APPL., vol. 655, 1994, pages 281 - 285, XP002961582
Download PDF: