Title:
SMALL MOLECULE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 1 (USP1) AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/083297
Kind Code:
A1
Abstract:
Provided are small molecules inhibitory compounds of ubiquitin specific protease 1 (USP1) and compositions comprising the same. Further provided are methods for targeting ubiquitin specific protease 1 (USP1) and methods of treating diseases or disorders related to USP1, such as cancers.
Inventors:
WU JIANPING (CN)
QIN LUOHENG (CN)
LIU JINXIN (CN)
LIU YINGTAO (CN)
QIN LUOHENG (CN)
LIU JINXIN (CN)
LIU YINGTAO (CN)
Application Number:
PCT/CN2022/131359
Publication Date:
May 19, 2023
Filing Date:
November 11, 2022
Export Citation:
Assignee:
INSILICO MEDICINE IP LTD (CN)
International Classes:
C07D417/14; A61K31/519; A61P35/00; C07D273/00; C07D291/08
Domestic Patent References:
| WO2022214053A1 | 2022-10-13 | |||
| WO2022216820A1 | 2022-10-13 | |||
| WO2017112777A1 | 2017-06-29 | |||
| WO2018237084A1 | 2018-12-27 |
Foreign References:
| CN1503797A | 2004-06-09 | |||
| JP2004083587A | 2004-03-18 |
Attorney, Agent or Firm:
AFD CHINA INTELLECTUAL PROPERTY LAW OFFICE (CN)
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