Title:
SOLID FORM OF COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/143479
Kind Code:
A1
Abstract:
Provided are a solid form of a compound, a preparation method therefor and the use thereof, which belong to the field of pharmaceutical chemistry. The solid form comprises a co-crystal of the compound and cinnamamide, or a tromethamine salt of the compound. The solid form of the compound has a good stability and solubility.
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Inventors:
XU JINCHAO (CN)
ZHANG JIE (CN)
YANG LIUHONG (CN)
ZHANG PENGWEI (CN)
YE HUIQING (CN)
CHEN YONG (CN)
HUANG FANGFANG (CN)
ZHANG JIE (CN)
YANG LIUHONG (CN)
ZHANG PENGWEI (CN)
YE HUIQING (CN)
CHEN YONG (CN)
HUANG FANGFANG (CN)
Application Number:
PCT/CN2021/141429
Publication Date:
July 07, 2022
Filing Date:
December 27, 2021
Export Citation:
Assignee:
SUNSHINE LAKE PHARMA CO LTD (CN)
International Classes:
A61K31/428; C07D419/12; A61P1/16
Domestic Patent References:
| WO2020021215A1 | 2020-01-30 |
Foreign References:
| CN101248044A | 2008-08-20 | |||
| CN109316601A | 2019-02-12 |
Other References:
BENAÏSSA BOUBIA; OLIVIA POUPARDIN; MARTINE BARTH; JEAN BINET; PHILIPPE PERALBA; LAURENT MOUNIER; ELISE JACQUIER; EMILIE GAUTHIER; : "Design, Synthesis, and Evaluation of a Novel Series of Indole Sulfonamide Peroxisome Proliferator Activated Receptor (PPAR) alpha/gamma/delta Triple Activators: Discovery of Lanifibranor, a New Antifibrotic Clinical Candidate", JOURNAL OF MEDICAL CHEMISTRY, vol. 61, no. 6, 22 March 2018 (2018-03-22), pages 2246 - 2265, XP002790345, DOI: 10.1021/acs.jmedchem.7b01285
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