Title:
SOLUBLE ACE2 AND FUSION PROTEIN, AND APPLICATIONS THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/170131
Kind Code:
A1
Abstract:
Soluble ACE2 and a truncated form thereof, a fusion protein thereof and preparation methods therefor. Soluble ACE2 and a truncated form thereof, as well as a use of the fusion protein in the preparation of a medicine for ACE2-related diseases.
Inventors:
LI WENHUI (CN)
QI YONGHE (CN)
CHEN JIANHE (CN)
SUI JIANHUA (CN)
LIU JUAN (CN)
MAO FENGFENG (CN)
LIU XIMING (CN)
QI YONGHE (CN)
CHEN JIANHE (CN)
SUI JIANHUA (CN)
LIU JUAN (CN)
MAO FENGFENG (CN)
LIU XIMING (CN)
Application Number:
PCT/CN2021/078343
Publication Date:
September 02, 2021
Filing Date:
February 27, 2021
Export Citation:
Assignee:
HUAHUI HEALTH LTD (CN)
NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN)
NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN)
International Classes:
C07K19/00; A61P9/00; A61P13/12; C07K16/00; C12N15/00; C12N15/62
Domestic Patent References:
| WO2018140456A1 | 2018-08-02 | |||
| WO2009023306A2 | 2009-02-19 |
Foreign References:
| CN102639147A | 2012-08-15 | |||
| CN1884303A | 2006-12-27 |
Other References:
ROBERT L. KRUSE: "Therapeutic strategies in an outbreak scenario to treat the novel coronavirus originating in Wuhan, China", F1000RESEARCH, F1000 RESEARCH LTD, GB, vol. 9, GB, pages 72, XP055737402, ISSN: 2046-1402, DOI: 10.12688/f1000research.22211.2
KLEINE-WEBER HANNAH, ELZAYAT MAHMOUD TAREK, HOFFMANN MARKUS, PÖHLMANN STEFAN: "Functional analysis of potential cleavage sites in the MERS-coronavirus spike protein", SCIENTIFIC REPORTS, NATURE PUBLISHING GROUP, US, vol. 8, no. 1, 1 December 2018 (2018-12-01), US, pages 16597 - 11, XP055840280, ISSN: 2045-2322, DOI: 10.1038/s41598-018-34859-w
HAN JIANFENG, JIANG TAO; CHEN SHUIPING; LI XIAOFENG; QIN CHENGFENG; YU MAN; QIN EDE: "Effects of spike gene mutation on infectivity of SARS-CoV BJ01 strain", JUNSHI YIXUE KEXUEYUAN YUANKAN - BULLETIN OF THE ACADEMY OFMILITARY MEDICAL SCIENCES, BEIJING,, CN, vol. 32, no. 2, 1 April 2008 (2008-04-01), CN, pages 106 - 110,120, XP055840294, ISSN: 1000-5501
KLEINE-WEBER HANNAH, ELZAYAT MAHMOUD TAREK, HOFFMANN MARKUS, PÖHLMANN STEFAN: "Functional analysis of potential cleavage sites in the MERS-coronavirus spike protein", SCIENTIFIC REPORTS, NATURE PUBLISHING GROUP, US, vol. 8, no. 1, 1 December 2018 (2018-12-01), US, pages 16597 - 11, XP055840280, ISSN: 2045-2322, DOI: 10.1038/s41598-018-34859-w
HAN JIANFENG, JIANG TAO; CHEN SHUIPING; LI XIAOFENG; QIN CHENGFENG; YU MAN; QIN EDE: "Effects of spike gene mutation on infectivity of SARS-CoV BJ01 strain", JUNSHI YIXUE KEXUEYUAN YUANKAN - BULLETIN OF THE ACADEMY OFMILITARY MEDICAL SCIENCES, BEIJING,, CN, vol. 32, no. 2, 1 April 2008 (2008-04-01), CN, pages 106 - 110,120, XP055840294, ISSN: 1000-5501
Attorney, Agent or Firm:
IPSUNNY (CN)
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