Title:
SPERM FERTILITY PROMOTER
Document Type and Number:
WIPO Patent Application WO/2020/013086
Kind Code:
A1
Abstract:
The present invention relates to a sperm fertility promoter comprising pyrroloquinoline quinone or a salt thereof.
Inventors:
SHIMADA MASAYUKI (JP)
Application Number:
PCT/JP2019/026748
Publication Date:
January 16, 2020
Filing Date:
July 04, 2019
Export Citation:
Assignee:
UNIV HIROSHIMA (JP)
ROHTO PHARMA (JP)
ROHTO PHARMA (JP)
International Classes:
A61K31/4745; A61P5/26; A61P13/08; A61P15/08; A61P43/00; A01N1/02
Foreign References:
| CN107174583A | 2017-09-19 | |||
| JPH01305016A | 1989-12-08 | |||
| JP2007274907A | 2007-10-25 |
Other References:
LI ZHILING ET AL.: "Protective Effects of Ascorbate and Catalase on Human Spermatozoa During Cryopreservation", JOURNAL OF ANDROLOGY, vol. 31, no. 5, September 2010 (2010-09-01), pages 437 - 444, XP055674947, ISSN: 0196-3635, DOI: 10.2164/jandrol.109.007849
TAG RONG ET AL.: "Pyrroloquinoline quinone preserves mitochondrial function and prevents oxidative injury in adult rat cardiac myocytes", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 363, no. 2, 2007, pages 257 - 262, XP022278074, ISSN: 0006-291X, DOI: 10.1016/j.bbrc.2007.08.041
MAHARJAN SUNITA ET AL.: "Screening of dietary antioxidants against mitochondria-mediated oxidative stress by visualization of intracellular redox state", BIOSCIENCE,BIOTECHNOLOGY,AND BIOCHEMISTRY, vol. 80, no. 4, 14 January 2016 (2016-01-14), pages 726 - 734, XP055674952, ISSN: 0916-8451, DOI: 10.1080/09168451.2015.1123607
TAG RONG ET AL.: "Pyrroloquinoline quinone preserves mitochondrial function and prevents oxidative injury in adult rat cardiac myocytes", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 363, no. 2, 2007, pages 257 - 262, XP022278074, ISSN: 0006-291X, DOI: 10.1016/j.bbrc.2007.08.041
MAHARJAN SUNITA ET AL.: "Screening of dietary antioxidants against mitochondria-mediated oxidative stress by visualization of intracellular redox state", BIOSCIENCE,BIOTECHNOLOGY,AND BIOCHEMISTRY, vol. 80, no. 4, 14 January 2016 (2016-01-14), pages 726 - 734, XP055674952, ISSN: 0916-8451, DOI: 10.1080/09168451.2015.1123607
Attorney, Agent or Firm:
HASEGAWA Yoshiki et al. (JP)
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