Title:
STABILIZER FOR AQUEOUS PROTEIN SOLUTION, AQUEOUS PROTEIN SOLUTION AND LIQUID DETERGENT COMPOSITION EACH CONTAINING THE STABILIZER, AND METHOD FOR STABILIZATION OF PROTEIN USING THE STABILIZER
Document Type and Number:
WIPO Patent Application WO/2011/024862
Kind Code:
A1
Abstract:
Disclosed are: a stabilizer for an aqueous solution of a protein, which can prevent the deterioration in physiological properties of the protein caused by the aggregation or the like of the protein in the aqueous solution and which can stabilize the aqueous solution of the protein for a long period; and a liquid detergent composition in which the enzymatic activity of an enzyme can be maintained satisfactorily and washing performance can be maintained for a long period. The stabilizer for an aqueous solution of a protein contains an organic compound (A) which fulfills the following requirements (1) to (3): (1) when a proton is added to the molecule of the organic compound (A), a π-bond formed by a π electron of at least one atom (Z) contained in the molecule and a π electron of an atom (Y) bound to the atom (Z) has a resonance structure in the atom (Z), and there is at least four π electrons which are shared between the atom (Z) and the atom (Y) and are involved in the π-bond having the resonance structure; (2) a 0.1 moldm-3 solution of the organic compound (A) has an ionic strength of 0.1 or more; and (3) the organic compound (A) has a molecular weight of less than 300.
Inventors:
YAMAGUCHI SHUNICHIRO (JP)
Application Number:
PCT/JP2010/064398
Publication Date:
March 03, 2011
Filing Date:
August 25, 2010
Export Citation:
Assignee:
SANYO CHEMICAL IND LTD (JP)
YAMAGUCHI SHUNICHIRO (JP)
YAMAGUCHI SHUNICHIRO (JP)
International Classes:
C12N9/96; C12N9/42
Domestic Patent References:
| WO1993016175A1 | 1993-08-19 |
Foreign References:
| JP2007006746A | 2007-01-18 | |||
| JP2009028034A | 2009-02-12 | |||
| JP2009034095A | 2009-02-19 |
Other References:
GANGADHARA B.N. ET AL.: "Enhancement of nuclease P1 activity in low concentration of denaturants", ENZYME MICROB. TECHNOL., vol. 43, 2008, pages 336 - 342, XP023979640, DOI: doi:10.1016/j.enzmictec.2008.05.009
Attorney, Agent or Firm:
YASUTOMI & Associates (JP)
Patent business corporation Yasutomi international patent firm (JP)
Patent business corporation Yasutomi international patent firm (JP)
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