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Title:
STABLE PHARMACEUTICAL PREPARATION
Document Type and Number:
WIPO Patent Application WO/2022/025660
Kind Code:
A1
Abstract:
A stable pharmaceutical preparation according to the present invention comprises: a recombinant fusion protein; a surfactant; a saccharide or a derivative thereof; and a buffer agent. The stable pharmaceutical preparation according to the present invention has a low viscosity while comprising a recombinant fusion protein, maintains excellent stability in long-term storage, accelerated, and severe conditions, and can be intraocularly administered.

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Inventors:
KIM SU JUNG (KR)
KIM KWANG WOO (KR)
ROH JI WON (KR)
SHIN YEON KYEONG (KR)
OH JUN SEOK (KR)
LEE JAE BIN (KR)
HAN WON YONG (KR)
Application Number:
PCT/KR2021/009870
Publication Date:
February 03, 2022
Filing Date:
July 29, 2021
Export Citation:
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Assignee:
CELLTRION INC (KR)
International Classes:
A61K9/08; A61K9/00; A61K38/00; A61K38/17; A61K47/10; A61K47/18; A61K47/22; A61K47/26; A61P27/02
Domestic Patent References:
WO2017129685A12017-08-03
Foreign References:
KR20200084897A2020-07-13
US6833349B22004-12-21
KR20170000356A2017-01-02
KR20200029374A2020-03-18
KR20090018807A2009-02-23
US4861335A1989-08-29
US6331174B12001-12-18
Other References:
See also references of EP 4190310A4
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