SUBSTITUTED BENZOYLAMINOTHIAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME

Title:

SUBSTITUTED BENZOYLAMINOTHIAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME

Document Type and Number:

WIPO Patent Application WO/1998/017654

Kind Code:

A1

Abstract:

Substituted benzoylaminothiazole derivatives represented by general formula (I) or salts thereof and drugs containing the same as the active ingredient. In said formula, X represents imino optionally substituted by lower alkyl, or oxygen; R?1� represents cyano, lower alkoxycarbonyl, lower alkoxycarbonyloxy, lower alkylsulfonylamino, optionally halogenated lower alkanoyl or lower alkylsulfonyl, 1-ureido, halogenated lower alkyl, or 2-pyrrolylimino; R?2� and R?3� are the same or different and each represents hydrogen or lower alkyl; and m is an integer of 2 to 4. Because of having an excellent effect of improving digestive motions, these compounds are useful as preventives and remedies for unidentified epigastric complaints, vomiturition, vomiting, heartburn, anorexia, abdominal pain, abdominal swelling feel, chronic gastritis, etc.

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Inventors:

NAGASAWA MASAAKI (JP)
SATO KENJI (JP)
KURIMOTO TADASHI (JP)
UEKI SHIGERU (JP)

Application Number:

PCT/JP1997/003774

Publication Date:

April 30, 1998

Filing Date:

October 20, 1997

Export Citation:

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Assignee:

ZERIA PHARM CO LTD (JP)
NAGASAWA MASAAKI (JP)
SATO KENJI (JP)
KURIMOTO TADASHI (JP)
UEKI SHIGERU (JP)

International Classes:

C07D277/46; C07D277/56; C07D417/12; (IPC1-7): C07D277/46; C07D277/56; C07D417/12; A61K31/425

Domestic Patent References:

WO1996036619A1	1996-11-21
WO1995011889A1	1995-05-04

Foreign References:

US5510478A	1996-04-23
JPH0987282A	1997-03-31
JPS6431424A	1989-02-01
JPH03163074A	1991-07-15
JPH04279581A	1992-10-05
JPH06306089A	1994-11-01

Other References: