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Title:
SUGAR CHAIN LIBRARY CONSTRUCTED VIA CARGO RECEPTOR GENE MODIFICATION
Document Type and Number:
WIPO Patent Application WO/2004/016789
Kind Code:
A1
Abstract:
A method of modifying a sugar chain of a sugar chain-binding protein; a sugar chain-binding protein having a modified sugar chain; cells expressing a modified sugar chain-binding protein and a method of constructing the same; and a process for producing a modified sugar chain-binding protein.

Inventors:
YAMAMOTO KAZUO (JP)
SATO AKIRA (JP)
SHIMAUCHI JUNKO (JP)
MATSUMOTO MARIKO (JP)
Application Number:
PCT/JP2003/001718
Publication Date:
February 26, 2004
Filing Date:
February 18, 2003
Export Citation:
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Assignee:
YAMAMOTO KAZUO (JP)
SUMITOMO CORP (JP)
SATO AKIRA (JP)
SHIMAUCHI JUNKO (JP)
MATSUMOTO MARIKO (JP)
International Classes:
C07H1/00; C07H3/00; C12N15/12; C12P21/00; (IPC1-7): C12N15/12; C12P21/02; C07K14/47; C07H1/00; C07H3/00; C12N5/10; C12Q1/02; G01N33/53
Other References:
YOKO HIRAI ET AL.: "VIP36 bunshi no kaihen ni yoru saibonai sorting katei no henka", NIHON YUAKUGAKKAI DAI 121 NENKAI YOSHISHU, 5 March 2001 (2001-03-05), pages 7, XP002975444
TAKAYO UENO ET AL.: "ERGIC-53 no kaihen ni okeru saibonai transport ni tsuite", NIHON YAKUGAKKAI DAI 121 NENKAI YOSHISHU, 5 March 2001 (2001-03-05), pages 9, XP002975445
YAMAMOTO K. ET AL.: "Cyborg lectins: novel leguminous lectins with unique specificaties", J. BIOCHEM., vol. 127, no. 1, January 2000 (2000-01-01), pages 137 - 142, XP002975446
YAMAMOTO K. ET AL.: "A chimeric lectin formed from Bauhinia purpurea lectin and lens culinaris lectin recognizes a unique carbohydrate structure", J. BIOCHEM., vol. 127, no. 1, January 2000 (2000-01-01), pages 129 - 135, XP002975447
YAMAMOTO K. ET AL.: "Analysis of asparagine-linked oligosaccharides by sequential lectin-affinity chromatography", METHODS MOL. BIOL., vol. 76, 1998, pages 35 - 51, XP002975448
HAURI H.P. ET AL.: "ERGIC-53 and traffic in the secretory pathway", J. CELL SCI., vol. 113, no. PT. 4, February 2000 (2000-02-01), pages 587 - 596, XP002975449
VELLOSO L.M. ET AL.: "Crystal structure of the carbohydrate recognition domain of p58/ERGIC-53, a protein involved in glycoprotein export from the endoplasmic reticulum", J. BIOL. CHEM., vol. 277, no. 18, 3 May 2002 (2002-05-03), pages 15979 - 15984, XP002975450
APPENZELLER C. ET AL.: "The lectin ERGIC-53 is a cargo transport receptor for glycoproteins", NAT. CELL BIOL., vol. 1, no. 6, 1999, pages 330 - 334, XP002975451
HAURI H. ET AL.: "Lectins and traffic in the secretory pathway", FEBS LETT., vol. 476, no. 1-2, 30 June 2000 (2000-06-30), pages 32 - 37, XP004337288
KAZUO YAMAMOTO: "Shokubutsu mame-ka lectin no tousa ninshiki kiko to cargo receptor kaihen ni yoru oyo", DAI 25 KAI THE MOLECULAR BIOLOGY SOCIETY OF JAPAN NENKAI PROGRAM-KOEN YOSHISHU, 25 November 2002 (2002-11-25), pages 410, XP002975452
Attorney, Agent or Firm:
Hiraki, Yusuke (Toranomon 4-chome Minato-ku, Tokyo, JP)
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