SULFAMIDE DERIVATIVE AND MEDICINAL COMPOSITION THEREOF

Title:

SULFAMIDE DERIVATIVE AND MEDICINAL COMPOSITION THEREOF

Document Type and Number:

WIPO Patent Application WO/2004/083167

Kind Code:

A1

Abstract:

A sulfamide derivative represented by the general formula (I): (I) (wherein R¹ to R⁸ each represents hydrogen, halogeno, etc.; and R⁹ or R¹⁰ represents hydrogen, optionally substituted alkyl, etc.) or a pharmacologically acceptable salt of the derivative; and a medicinal composition which comprises a combination of a sulfamide derivative represented by the general formula (I) (wherein R¹ to R⁸ each represents hydrogen, halogeno, etc.; and R⁹ or R¹⁰ represents hydrogen, optionally substituted alkyl, etc.) or pharmacologically acceptable salt of the derivative and a compound represented by the general formula (IV): (IV) (wherein X represents a cyclic benzimidazole group; Y¹ represents oxygen, etc.; Z represents 2,4-dioxothiazolidin-5-ylmethyl, etc.; R represents hydrogen, C_1-6 alkyl, etc.; and m is an integer of 1 to 5) or the like. This composition is used in such a manner that the two ingredients are administered either simultaneously or separately at an interval.

Inventors:

SHIBATA TOMOYUKI (JP)
IWADARE HAYATO (JP)
KIGA MASAKI (JP)
SHIMAZAKI NAOMI (JP)
ECHIGO TOMOKI (JP)
FUJIWARA KOSAKU (JP)
TANZAWA FUMIE (JP)

Application Number:

PCT/JP2004/003696

Publication Date:

September 30, 2004

Filing Date:

March 18, 2004

Export Citation:

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Assignee:

SANKYO CO (JP)
SHIBATA TOMOYUKI (JP)
IWADARE HAYATO (JP)
KIGA MASAKI (JP)
SHIMAZAKI NAOMI (JP)
ECHIGO TOMOKI (JP)
FUJIWARA KOSAKU (JP)
TANZAWA FUMIE (JP)

International Classes:

A61P3/10; A61P9/04; A61P9/10; A61P11/06; A61P25/28; A61P29/00; A61P31/12; A61P35/00; A61P37/06; C07D295/13; C07D295/26; C07D491/107; (IPC1-7): C07C307/10; A61K31/18; A61K31/40; A61K31/4409; A61K31/443; A61K31/445; A61K31/4453; A61K31/4468; A61K31/45; A61K31/4525; A61K31/4535; A61K31/454; A61K31/4545; A61K31/495; A61K31/496; A61K31/5375; A61K31/5377; A61P3/10; A61P9/04; A61P9/10; A61P11/06; A61P25/28; A61P29/00; A61P31/12; A61P35/00; A61P37/06; C07C311/32; C07C311/37; C07C323/48; C07D207/48; C07D211/58; C07D211/62; C07D211/96; C07D295/20; C07D295/22; C07D401/04; C07D401/12; C07D405/12; C07D409/12; C07D491/107

Foreign References:

JP2002293768A	2002-10-09
JP2002020362A	2002-01-23
JPH11510813A	1999-09-21

Attorney, Agent or Firm:

Ohno, Akio c/o Sankyo Company (Limited 2-58, Hiromachi 1-chom, Shinagawa-ku Tokyo 10, JP)

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