Title:
SUPERCOILED MINICIRCLE DNA AS AS A UNITARY PROMOTER VECTOR
Document Type and Number:
WIPO Patent Application WO1994009127
Kind Code:
A3
Inventors:
ADHYA SANKAR L (US)
CHOY HYON E (US)
CHOY HYON E (US)
Application Number:
PCT/US1993/009918
Publication Date:
June 09, 1994
Filing Date:
October 15, 1993
Export Citation:
Assignee:
US HEALTH (US)
International Classes:
C12N15/10; C12N15/70; (IPC1-7): C12N15/10; C12N1/21; C12N15/70
Other References:
K. BACKMAN ET AL.: "Use of synchronous site-specific recombination in vivo to regulate gene expression", BIO/TECHNOLOGY, vol. 2, no. 12, December 1984 (1984-12-01), NATURE AMERICA, INC., NEW YORK, US;, pages 1045 - 1049
A.J. PODHAJSKA ET AL.: "Control of cloned gene expression by promoter inversion in vivo: construction of the heat-pulse-activated att-nutL-p-att-N module", GENE, vol. 40, no. 1, 1985, ELSEVIER PUBLISHERS, N.Y., U.S.;, pages 163 - 168
R. HABER AND S. ADHYA: "Interaction of spatially separated protein-DNA complexes for control of gene expression: Operator conversions", PROC. NATL. ACAD SCI., vol. 85, no. 24, December 1988 (1988-12-01), NATL. ACAD SCI., WASHINGTON, DC, US;, pages 9683 - 9687
WATSON, HOPKINS,ROBERTS STEITZ,WEINER, MOLECULAR BIOLOGY OF THE GENE, FOURTH EDITION, 1987, BENJAMIN/CUMMINGS PUBL. COMP. INC.,MENLO PARK, CA,US;
N. HASAN AND W. SZYBALSKI: "Control of cloned gene expression by promoter inversion in vivo; construction of improved vectors with a multiple cloning site and the ptac promoter", GENE, vol. 56, no. 1, 1987, ELSEVIER PUBLISHERS, N.Y., U.S.;, pages 145 - 151
H.E. CHOY AND S. ADHYA: "Control of gal transcription through DNA looping: Inhibition of the initial transcription complex", PROC. NATL. ACAD SCI., vol. 89, no. 23, 1 December 1992 (1992-12-01), NATL. ACAD SCI., WASHINGTON, DC, US;, pages 11264 - 11268
H.E. CHOY AND S. ADHYA: "RNA polymerase idling and clearance in gal promoters: Use of supercoiled minicircle DNA template made in vivo", PROC. NATL. ACAD SCI., vol. 90, no. 2, 15 January 1993 (1993-01-15), NATL. ACAD SCI., WASHINGTON, DC, US;, pages 472 - 476
A.J. PODHAJSKA ET AL.: "Control of cloned gene expression by promoter inversion in vivo: construction of the heat-pulse-activated att-nutL-p-att-N module", GENE, vol. 40, no. 1, 1985, ELSEVIER PUBLISHERS, N.Y., U.S.;, pages 163 - 168
R. HABER AND S. ADHYA: "Interaction of spatially separated protein-DNA complexes for control of gene expression: Operator conversions", PROC. NATL. ACAD SCI., vol. 85, no. 24, December 1988 (1988-12-01), NATL. ACAD SCI., WASHINGTON, DC, US;, pages 9683 - 9687
WATSON, HOPKINS,ROBERTS STEITZ,WEINER, MOLECULAR BIOLOGY OF THE GENE, FOURTH EDITION, 1987, BENJAMIN/CUMMINGS PUBL. COMP. INC.,MENLO PARK, CA,US;
N. HASAN AND W. SZYBALSKI: "Control of cloned gene expression by promoter inversion in vivo; construction of improved vectors with a multiple cloning site and the ptac promoter", GENE, vol. 56, no. 1, 1987, ELSEVIER PUBLISHERS, N.Y., U.S.;, pages 145 - 151
H.E. CHOY AND S. ADHYA: "Control of gal transcription through DNA looping: Inhibition of the initial transcription complex", PROC. NATL. ACAD SCI., vol. 89, no. 23, 1 December 1992 (1992-12-01), NATL. ACAD SCI., WASHINGTON, DC, US;, pages 11264 - 11268
H.E. CHOY AND S. ADHYA: "RNA polymerase idling and clearance in gal promoters: Use of supercoiled minicircle DNA template made in vivo", PROC. NATL. ACAD SCI., vol. 90, no. 2, 15 January 1993 (1993-01-15), NATL. ACAD SCI., WASHINGTON, DC, US;, pages 472 - 476
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