Title:
SYNTHESIS METHOD FOR EASILY-SOLUBLE GUANIDINOACETIC ACID COMPLEX
Document Type and Number:
WIPO Patent Application WO/2023/241117
Kind Code:
A1
Abstract:
A synthesis method for an easily-soluble guanidinoacetic acid complex, comprising: first, adding guanidine hydrochloride into an alkaline solution A to generate free guanidine and obtain a solution B; then dropwise adding chloroacetic acid into the solution B to obtain a mixed solution C; finally, mixing an acidic substance D with the mixed solution C, and carrying out vacuum distillation to obtain a guanidinoacetic acid complex. The guanidinoacetic acid is crystallized in the form of a complex salt of the acidic substance D, so as to obtain a guanidinoacetic acid complex having high solubility and capable of being stored in a solid phase form.
Inventors:
LIN YAN (CN)
YANG LIBIN (CN)
YANG LIBIN (CN)
Application Number:
PCT/CN2023/080184
Publication Date:
December 21, 2023
Filing Date:
March 08, 2023
Export Citation:
Assignee:
BEIJING GENDONE BIOTECHNOLOGY CO LTD (CN)
International Classes:
C07C51/41; C07C277/08; C07C59/265; C07C279/14
Foreign References:
| CN101132786A | 2008-02-27 | |||
| CN101525305A | 2009-09-09 | |||
| CN102850241A | 2013-01-02 | |||
| CN104605161A | 2015-05-13 | |||
| CN1964633A | 2007-05-16 | |||
| JPS56111695A | 1981-09-03 |
Attorney, Agent or Firm:
BEIJING ZHCC INTELLECTUAL PROPERTY CO., LTD (CN)
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