Title:
SYSTEMICALLY-ACTING EXTERNAL PREPARATION CONTAINING SIROLIMUS OR DERIVATIVE THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/184131
Kind Code:
A1
Abstract:
[Problem] The present invention addresses the problem of providing an external preparation whereby sirolimus or a sirolimus derivative is absorbed transdermally or transmucosally into the blood and exerts an effect on the entire body. [Solution] Provided is an external preparation containing at least one selected from the group consisting of sirolimus and sirolimus derivatives, and vegetable oil. This external preparation has an active ingredient that passes through the skin or mucosa and migrates efficiently into the blood, and the rate of delivery of the active ingredient to the blood is substantially equivalent to that of an oral formulation.
Inventors:
KANEDA MARI (JP)
KATAYAMA ICHIRO (JP)
KATAYAMA ICHIRO (JP)
Application Number:
PCT/JP2020/006722
Publication Date:
September 17, 2020
Filing Date:
February 20, 2020
Export Citation:
Assignee:
UNIV OSAKA (JP)
International Classes:
A61P17/00; A61K31/436; A61K31/706; A61K47/44
Domestic Patent References:
| WO2016114216A1 | 2016-07-21 | |||
| WO2012105521A1 | 2012-08-09 |
Foreign References:
| CN1919194A | 2007-02-28 | |||
| CN105663027A | 2016-06-15 |
Attorney, Agent or Firm:
SHOJI Takashi et al. (JP)
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