Title:
TISSUE-ENGINEERING BONE SCAFFOLD AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2020/258828
Kind Code:
A1
Abstract:
A tissue-engineering bone scaffold and a preparation method therefor. The preparation method comprises the following steps: a cleaning step (S100): cleaning a tissue-engineering bone material by using a supercritical fluid, so as to remove soft tissues in the bone material to obtain an initial bone matrix; a sterilization step (S200): sterilizing the initial bone matrix by using the supercritical fluid to obtain a bone matrix; and a compounding step (S300): compounding cytokines inside holes of the bone matrix by means of the supercritical fluid to obtain a bone scaffold.
Inventors:
GUO QUANYI (CN)
LUO XUJIANG (CN)
LU SHIBI (CN)
LIU SHUYUN (CN)
SUI XIANG (CN)
HUANG JINGXIANG (CN)
HAN GANG (CN)
LUO XUJIANG (CN)
LU SHIBI (CN)
LIU SHUYUN (CN)
SUI XIANG (CN)
HUANG JINGXIANG (CN)
HAN GANG (CN)
Application Number:
PCT/CN2020/070708
Publication Date:
December 30, 2020
Filing Date:
January 07, 2020
Export Citation:
Assignee:
CHINESE PLA GENERAL HOSPITAL (CN)
International Classes:
A61L27/50; A61L27/36; A61L27/54; A61L27/56
Foreign References:
| CN110152067A | 2019-08-23 | |||
| US9649408B1 | 2017-05-16 | |||
| CN1476907A | 2004-02-25 | |||
| CN107722331A | 2018-02-23 | |||
| CN1090206A | 1994-08-03 |
Other References:
XIAN, HAI, LUZHOU YI XUE YUAN XUE BAO: "Application of Composite Technology Based on Supercritical Carbon Dioxide Extraction in Vitro Processing of Allograft Bones", JOURNAL OF SOUTHWEST MEDICAL UNIVERSITY, vol. 41, no. 3, 13 June 2018 (2018-06-13), pages 205 - 209, XP055770877, ISSN: 1000-2669, DOI: 10.3969/j.issn.2096-3351.2018.03.004
Attorney, Agent or Firm:
BEIJING EAST IP LTD. (CN)
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