Title:
TOMM34 PEPTIDES AND VACCINES INCLUDING THE SAME
Document Type and Number:
WIPO Patent Application WO/2012/073459
Kind Code:
A1
Abstract:
The present invention provides isolated peptides or the fragments derived from SEQ ID NO: 42, which bind to an HLA antigen and induce cytotoxic T lymphocytes (CTL). The peptides may include one of the above mentioned amino acid sequences with substitution, deletion, or addition of one, two, or several amino acids sequences. The present invention also provides pharmaceutical compositions including these peptides. The peptides of this invention can be used for treating cancer.
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Inventors:
NAKAMURA YUSUKE (JP)
TSUNODA TAKUYA (JP)
OSAWA RYUJI (JP)
YOSHIMURA SACHIKO (JP)
WATANABE TOMOHISA (JP)
NAKAYAMA GAKU (JP)
TSUNODA TAKUYA (JP)
OSAWA RYUJI (JP)
YOSHIMURA SACHIKO (JP)
WATANABE TOMOHISA (JP)
NAKAYAMA GAKU (JP)
Application Number:
PCT/JP2011/006551
Publication Date:
June 07, 2012
Filing Date:
November 25, 2011
Export Citation:
Assignee:
ONCOTHERAPY SCIENCE INC (JP)
NAKAMURA YUSUKE (JP)
TSUNODA TAKUYA (JP)
OSAWA RYUJI (JP)
YOSHIMURA SACHIKO (JP)
WATANABE TOMOHISA (JP)
NAKAYAMA GAKU (JP)
NAKAMURA YUSUKE (JP)
TSUNODA TAKUYA (JP)
OSAWA RYUJI (JP)
YOSHIMURA SACHIKO (JP)
WATANABE TOMOHISA (JP)
NAKAYAMA GAKU (JP)
International Classes:
C12N15/00; A61K38/00; A61K39/00; A61P35/00; A61P35/04; A61P37/04; C07K7/06; C07K16/32; C12N1/15; C12N1/19; C12N1/21; C12N5/0783; C12N5/0784; C12N5/10; G01N33/574
Domestic Patent References:
| WO2007013576A1 | 2007-02-01 | |||
| WO2003104275A2 | 2003-12-18 | |||
| WO2004024766A1 | 2004-03-25 | |||
| WO2008126413A1 | 2008-10-23 |
Other References:
HAZAMA, S. ET AL.: "Novel Vaccine Strategies for Colorectal Cancer", BIOTHERAPY, vol. 23, no. 2, 2009, pages 160 - 164, XP008168876
OKUNO, K. ET AL.: "Phase I clinical trial of a novel peptide vaccine in combination with UFT/LV for metastatic colorectal cancer", EXPERIMENTAL AND THERAPEUTIC MEDICINE, vol. 2, February 2011 (2011-02-01), pages 73 - 79, XP055108898
See also references of EP 2646546A4
OKUNO, K. ET AL.: "Phase I clinical trial of a novel peptide vaccine in combination with UFT/LV for metastatic colorectal cancer", EXPERIMENTAL AND THERAPEUTIC MEDICINE, vol. 2, February 2011 (2011-02-01), pages 73 - 79, XP055108898
See also references of EP 2646546A4
Attorney, Agent or Firm:
SHIMIZU, Hatsushi et al. (1-1-1 Oroshi-machi, Tsuchiura-sh, Ibaraki 47, JP)
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Claims: